The Biggest NFL Upsets in the Wild Card Round - 2025

Looking for upsets? More than one team overcame the odds in the NFL Wild Card round. Find out more about those underdogs who were victorious in the article below.

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NFL Wild Card Round's Biggest Upsets

49ers 23, Eagles 19

• Spread: Eagles -5.5
• Total: Under (44)
• Moneyline: Eagles -250, 49ers +200

Bears 31, Packers 27

• Spread: Packers -2
• Total: Over (46.5)
• Moneyline: Packers -130, Bears +110

Bills 27, Jaguars 24

• Spread: Jaguars -1.5
• Total: Under (51.5)
• Moneyline: Jaguars -120, Bills +100

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.