Patriots vs. Raiders 2025 Prediction, Odds, Picks - Sep 7

The New England Patriots (0-0) are considered favorites (-2.5) according to the oddsmakers ahead of their game against the Las Vegas Raiders (0-0) on September 7, 2025, starting at 1 p.m. ET, airing on CBS. An over/under of 44.5 points has been established for the matchup.

Keep up with the 2025 NFL season on FOX Sports.

Nick's Picks: Chiefs an 'easy bet,' Raiders upset Patriots, Bills beat Ravens in Week 1 | First Things First

Nick Wright unveils his favorite Week 1 picks, including the Las Vegas Raiders upsetting the New England Patriots.

Patriots vs. Raiders Odds & Betting Lines

Patriots vs. Raiders Prediction & Pick

• Pick ATS: Raiders (+2.5)
  
• Pick OU: Under (44.5)
  
• Prediction: Patriots 22 - Raiders 21

How to Watch New England vs. Las Vegas

• Game date: Sunday, September 7, 2025
• Time: 1 p.m. ET
• Venue: Gillette Stadium
• Location: Foxborough, Massachusetts
• TV: CBS
• Live Boxscore: FOX Sports

Patriots vs. Raiders Recent Matchups

• Over their last three meetings, Las Vegas has two wins versus New England.
• Las Vegas has been outpaced by 15 points in its last three tilts against New England.

New England Betting Info

• New England won seven games against the spread last season, failing to cover or pushing 10 times.
• Last season, 11 New England games went over the point total.
• The Patriots never played as the moneyline favorite in a game last season.
• New England did not play a game last season with moneyline odds of -155 or shorter.
• Based on this game's moneyline, the Patriots' implied win probability is 60.8%.

Patriots Stats (2024)

New England's Key Players

Offense

• In 13 games played last year, Drake Maye racked up 2,276 passing yards, while throwing 15 touchdowns against 10 interceptions and completing 66.6% of his passes.
• On the ground, Maye added two rushing touchdowns and 421 rushing yards.
• Rhamondre Stevenson had 801 rushing yards and seven rushing touchdowns, while averaging 53.4 yards per game and 3.9 per attempt (36th in the NFL).
• Stevenson added 33 receptions (2.2 per game) for 168 yards (11.2 per game) with one receiving touchdown. He was targeted 41 times in the passing game.
• In 16 games played last season, Demario Douglas had 66 catches (4.1 receptions per game on 5.4 targets per game) for 621 yards and three receiving touchdowns.
• Kayshon Boutte had 589 receiving yards and three touchdowns from 43 receptions on 68 targets.

Defense

• Robert Spillane intercepted two passes to go with 158 tackles, 10 TFL, two sacks, and seven passes defended for the Raiders in 2024.
• Harold Landry had 71 tackles, 15 TFL, and nine sacks for the Titans.
• Keion White had five sacks in addition to his seven TFL and 56 tackles.
• Anfernee Jennings' stats included 78 tackles, seven TFL, 2.5 sacks, and one pass defended in 16 games

Las Vegas Betting Info

• Las Vegas covered seven times in 17 chances against the spread last year.
• The Raiders had an ATS record of 5-8-1 as underdogs of 2.5 points or more last year.
• In Las Vegas games last season, combined scoring went over the point total nine times.
• Last season, the Raiders won two out of the 14 games, or 14.3%, in which they were the underdog.
• Las Vegas had a record of 1-10 in games where oddsmakers had them as underdogs of at least +130 on the moneyline.
• The oddsmakers' moneyline implies a 43.5% chance of a victory for the Raiders.

Raiders Stats (2024)

Las Vegas' Key Players

Offense

• Geno Smith passed for 4,320 yards last year for the Seahawks (fourth in NFL), with 21 TDs and 15 INTs. He completed 70.4% of his passes, averaging 254.1 yards per game and 7.5 per attempt.
• He added 272 yards on the ground, with two rushing TDs. He averaged 16 yards per game and 5.1 per attempt.
• Brock Bowers had 1,194 yards receiving (eighth in the NFL) and five TDs on 112 catches (third in the NFL), and was targeted 153 times.
• In 15 games last season, Jakobi Meyers had 87 catches (5.8 per game on 8.6 targets per game) for 1,027 yards and four TDs.
• Tre Tucker had 539 yards receiving and three TDs via 47 catches on 81 targets.

Defense

• Germaine Pratt put up five TFL, 143 tackles, and two interceptions in 17 games for the Bengals during the 2024 season.
• Jeremy Chinn put up one interception on top of 107 tackles, seven TFL, two sacks, and five passes defended for the Commanders.
• Maxx Crosby recorded 7.5 sacks and 17 TFL and 45 tackles during the 2024 campaign.
• Isaiah Pola-Mao put up one sack plus two TFL and 85 tackles in 16 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

New England Patriots

Las Vegas Raiders