Thunder vs. Grizzlies Prediction, Odds, Picks - Dec. 22

The Memphis Grizzlies (13-15) go up against the Oklahoma City Thunder (25-3) on December 22, 2025 at Paycom Center. The Thunder are currently huge 15.5-point favorites against the Grizzlies. The over/under is 233.5 points for the matchup.

Here is everything you need to know to know about the Thunder-Grizzlies game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Thunder vs. Grizzlies Game Information, TV Channel & Odds

• When: Monday, December 22, 2025 at 9:30 p.m. ET
• Where: Paycom Center in Oklahoma City, Oklahoma
• TV: Peacock and FDSOK
• Live Boxscore: FOX Sports

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Thunder vs. Grizzlies Prediction

ATS Pick: Thunder (- 15.5)
O/U Pick: Under (233.5)
Score Prediction: Thunder 123 - Grizzlies 107

Thunder vs. Grizzlies Betting Insights

• The Thunder and their opponent have combined to score over 233.5 points, the current matchup's total, in 11 of 28 games this year.
• Nine of the Grizzlies' 28 games this season have gone over 233.5 total points scored.
• Between them, these two teams average 3.7 more points per game (237.2) than this matchup's over/under (233.5).
• The Thunder and the Grizzlies have seen their opponents average a combined 11.4 fewer points per game than the over/under of 233.5 set for this outing.
• Oklahoma City has been the favorite in 28 games this season and has come away with the win 25 times (89.3%) in those contests.
• Memphis has been victorious in five, or 29.4%, of the 17 contests it has been chosen as an underdog in this season.
• Oklahoma City has won its one head-to-head matchup against Memphis.
• The Thunder also have a 1-0 record against the spread when taking on the Grizzlies.

Thunder Recent Trends

• The Thunder are 5-5 against the spread and 8-2 overall over their last 10 games.
• Oklahoma City and its opponents have combined to score an average of 227.7 points over its last 10 games, 5.8 less than the 233.5 over/under in this matchup.
• In the Thunder's 28 games this season, they have 15 wins against the spread.
• So far this season, Oklahoma City has been installed as favorites by a 15.5-point margin or more nine times and are 6-3 ATS in those games.
• Thunder games this year have gone over the point total 15 times in 28 opportunities (53.6%).
• The 122.5 points per game the Thunder average are 6.8 more points than the Grizzlies allow (115.7).
• When Oklahoma City totals more than 115.7 points, it is 14-6 against the spread and 19-1 overall.
• This season, the Thunder have a 49.2% shooting percentage from the field, which is 2.5% higher than the 46.7% of shots the Grizzlies' opponents have knocked down.
• The Thunder own a better record against the spread when playing at home (8-6-0) than they do in away games (7-7-0).
• Oklahoma City has eclipsed the total in a higher percentage of games at home (57.1%) than away games (50%).
• At home, the Thunder have won more often as a moneyline favorite, producing a record of 13-1 (.929). In road games, they are 12-2 (.857) as a moneyline favorite.

Thunder Recent Stats

Thunder Leaders

• Shai Gilgeous-Alexander posts 32.5 points, 6.4 assists and 4.7 rebounds per game.
• Ajay Mitchell averages 14.1 points, 3.4 rebounds and 3.6 assists per contest. At the other end, he averages 1.4 steals and 0.3 blocks.
• Cason Wallace puts up 8 points, 3 rebounds and 2.4 assists per game. Defensively, he averages 2.4 steals (first in league) and 0.2 blocks.
• Isaiah Joe posts 12.6 points, 2.9 boards and 1.6 assists per game. Defensively, he averages 0.6 steals and 0.2 blocks.
• Aaron Wiggins puts up 11.9 points, 3.1 rebounds and 1.8 assists per game, shooting 45.6% from the field and 40.7% from downtown with 2.2 made treys per contest.

Thunder Player Props

Grizzlies Recent Trends

• The Grizzlies are 7-3 against the spread and 7-3 overall over their last 10 games.
• Memphis has averaged a total of 231.4 combined points in its last 10 games, 2.1 less than this game's total of 233.5.
• In the Grizzlies' 28 games this year, they have 13 wins against the spread.
• Grizzlies games this season have hit the over on 10 of 28 set point totals (35.7%).
• The Grizzlies put up 8.3 more points per game (114.7) than the Thunder give up (106.4).
• When it scores more than 106.4 points, Memphis is 11-10 against the spread and 12-9 overall.
• The Grizzlies are shooting 45.2% from the field, 2.6% higher than the 42.6% the Thunder's opponents have shot this season.
• The Grizzlies' winning percentage against the spread at home is .429 (6-8-0). Away, it is .500 (7-7-0).
• Looking at the over/under, Memphis' games have gone over six of 14 times at home (42.9%), and four of 14 away (28.6%).
• As moneyline favorites, the Grizzlies have won a lower percentage of games at home (5-3) than away (3-0).

Grizzlies Recent Stats

Grizzlies Leaders

• Santi Aldama is putting up 13.8 points, 6.6 rebounds and 2.9 assists per game. He's also sinking 48.2% of his shots from the field and 34.1% from beyond the arc, with 1.5 triples per contest.
• On a per-game basis, Jaren Jackson Jr. gets the Grizzlies 18 points, 5.3 rebounds and 2.1 assists. He also averages 0.9 steals and 1.2 blocked shots.
• Cedric Coward is putting up 13.4 points, 6.2 rebounds and 2.8 assists per game. He is making 46.3% of his shots from the field and 31.5% from 3-point range, with 1.4 triples per contest.
• Jock Landale is putting up 10.8 points, 5.7 rebounds and 1.6 assists per game. He is making 51.5% of his shots from the floor and 41.3% from 3-point range, with 1.1 treys per contest.
• The Grizzlies are getting 12.3 points, 2.2 rebounds and 4.2 assists per game from Cam Spencer this season.

Grizzlies Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.