Pistons vs. 76ers Prediction, Odds, Picks - Nov. 14

Two of the league's best scorers -- Cade Cunningham (10th, 27.5 points per game) and Tyrese Maxey (third, 32.1) -- hit the court when the Detroit Pistons (10-2) host the Philadelphia 76ers (7-4) on November 14, 2025 on FDSDET and NBCS-PH. The Pistons are currently 4.5-point favorites over the 76ers. The point total for the matchup is 230.5.

Here is everything you need to know to know about the Pistons-76ers game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Pistons vs. 76ers Game Information, TV Channel & Odds

• When: Friday, November 14, 2025 at 7:30 p.m. ET
• Where: Little Caesars Arena in Detroit, Michigan
• TV: FDSDET and NBCS-PH
• Live Boxscore: FOX Sports

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Pistons vs. 76ers Prediction

ATS Pick: 76ers (+ 4.5)
O/U Pick: Over (230.5)
Score Prediction: Pistons 119 - 76ers 115

Pistons vs. 76ers Betting Insights

• This season, the Pistons games have gone over 230.5 points scored, their current matchup's point total, six (out of 12) times.
• This year, seven of the 76ers' 11 games have had a combined total higher than 230.5 points scored.
• These teams average 239 points per game combined, 8.5 more than the total of 230.5.
• Opponents of these two teams have averaged a combined 229.6 points per game, 0.9 fewer than the point total in this game.
• Detroit has won seven of the eight contests in which it was the favorite this year.
• Philadelphia has been victorious in three of the seven contests it has been chosen as an underdog in this season.
• Detroit has a 1-0 record in the last one head-to-head matchups against Philadelphia.
• The 76ers have a 1-0 record against the spread when facing the Pistons.
• The 76ers have covered the point spread in their past three games, and were favored in one of them.

Pistons Recent Trends

• The Pistons have played 12 games, with eight wins against the spread.
• Detroit is 4-2 ATS when favored by 4.5 points or more this season.
• The Pistons have eclipsed the over/under in 54.5% of their opportunities this year (six times over 11 games with a set point total).
• The 118.5 points per game the Pistons record are only 1.7 more points than the 76ers give up (116.8).
• Detroit is 5-1 against the spread and 6-0 overall when scoring more than 116.8 points.
• This season, the Pistons have a 47.4% shooting percentage from the field, which is 0.6% higher than the 46.8% of shots the 76ers' opponents have knocked down.
• The Pistons have done a better job covering the spread at home (5-2-0) than they have in road games (3-2-0).
• Detroit has hit the over on the over/under in a higher percentage of home games (71.4%) than away games (20%).
• When playing at home, the Pistons have won more consistently as a moneyline favorite, producing a record of 4-0 (1.000). When playing on the road, they are 3-1 (.750) as a moneyline favorite.

Pistons Recent Stats

Pistons Leaders

• Cunningham averages 27.5 points, 5.4 rebounds and 9.9 assists per game. At the other end, he averages 1.4 steals and 0.8 blocks.
• Jalen Duren posts 19.4 points, 12 rebounds and 1.6 assists per game, shooting 64.7% from the floor (seventh in NBA).
• Duncan Robinson averages 12.3 points, 1.7 assists and 2.6 boards per game.
• Ron Holland II posts 9.3 points, 3.8 rebounds and 1.8 assists per contest, shooting 40.4% from the field and 31% from beyond the arc with 1.1 made 3-pointers per contest.
• Isaiah Stewart puts up 10.7 points, 6.7 rebounds and 1.6 assists per contest, shooting 48.6% from the field and 39.3% from beyond the arc with 1.2 made treys per contest.

Pistons Player Props

76ers Recent Trends

• The 76ers have played 11 games, with seven wins against the spread.
• This season, Philadelphia has an against-the-spread record of 3-1 in its four games as an underdog of 4.5 points or more.
• 76ers games this year have gone over the point total 63.6% of the time (seven out of 11 games with a set point total).
• The 76ers score an average of 120.5 points per game, 7.7 more points than the 112.8 the Pistons give up to opponents.
• When it scores more than 112.8 points, Philadelphia is 5-2 against the spread and 6-1 overall.
• The 76ers are shooting 46.9% from the field, 3.1% higher than the 43.8% the Pistons' opponents have shot this season.
• This season, the 76ers are 4-1-1 at home against the spread (.667 winning percentage). Away, they are 3-2-0 ATS (.600).
• In 2025-26 a lower percentage of Philadelphia's games have finished above the over/under at home (50%, three of six) compared to on the road (80%, four of five).
• The 76ers, when moneyline favorites, have won the same percentage of games at home (2-0) and on the road (2-0) this season.

76ers Recent Stats

76ers Leaders

• On a per-game basis, Maxey gives the 76ers 32.1 points, 4.9 rebounds and 8.3 assists. He also averages 1.2 steals and 0.9 blocked shots.
• VJ Edgecombe is putting up 15.4 points, 5.5 rebounds and 4.3 assists per game. He's sinking 40.9% of his shots from the field and 36.2% from 3-point range, with 1.9 triples per contest.
• Kelly Oubre Jr. is averaging 18 points, 5.5 rebounds and 1.4 assists per contest. He is making 50.7% of his shots from the field and 35.4% from 3-point range, with 2.1 treys per contest.
• Quentin Grimes is averaging 17.3 points, 4.3 rebounds and 4.4 assists per contest. He is making 48% of his shots from the field and 40.6% from 3-point range, with 2.5 triples per game.
• Andre Drummond is averaging 7.6 points, 8.6 rebounds and 0.7 assists per contest. He is sinking 56.6% of his shots from the floor.

76ers Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

FOLLOW Follow your favorites to personalize your FOX Sports experience

National Basketball Association

Detroit Pistons

Philadelphia 76ers