Yankees vs. Guardians Prediction, Odds, Picks - June 5

Slade Cecconi will take the mound for the Cleveland Guardians against Paul Goldschmidt and the New York Yankees on Thursday at 7:05 p.m. ET. The Yankees are the favorite in this one, at -275, while the underdog Guardians have +223 odds to play spoiler. New York is favored on the run line (-1.5). The over/under is 8.5 runs for the matchup.

Check out everything you need to know from a betting perspective on the Yankees-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Yankees Highlights | MLB on FOX

Check out the best moments between the Cleveland Guardians and the New York Yankees.

Yankees vs. Guardians Game Information & Odds

• When: Thursday, June 5, 2025 at 7:05 p.m. ET
• Where: Yankee Stadium in The Bronx, New York
• How to watch on TV: MLB Network, YES, and CLEG

Yankees vs. Guardians Prediction

• Score Prediction: Yankees 4, Guardians 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Yankees 59%, Guardians 41%

Yankees vs. Guardians Betting Insights

• This season, the Yankees have been favored 52 times and won 34, or 65.4%, of those games.
• New York has a record of 2-1 in games when bookmakers favor them by at least -275 on the moneyline.
• The Yankees have a 73.3% chance to win this game based on the implied probability of the moneyline.
• The Guardians have come away with 18 wins in the 36 contests they have been listed as the underdogs in this season.
• Cleveland has played as an underdog of +223 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies the Guardians have a 31% chance of walking away with the win.

Yankees Recent Betting Performance

• The Yankees were favored on the moneyline for nine of their last 10 games, and they finished 6-3 in those matchups.
• In their last 10 matchups, the Yankees and their opponents combined to go over the run total four times (all 10 of the games had set totals).
• The Yankees are 3-7-0 against the spread over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Aaron Judge paces the Yankees with 21 home runs and 50 runs batted in, while accumulating a team-high batting average of .389.
• In all of the majors, Judge ranks third in homers and fifth in RBI.
• Paul Goldschmidt is hitting .323 with 13 doubles, a triple, six home runs and 19 walks.
• Goldschmidt is 117th in home runs and 81st in RBI among all MLB hitters this year.
• Cody Bellinger is batting .252 with 10 doubles, two triples, eight home runs and 24 walks.
• Bellinger is on a two-game hitting streak entering this contest. During his last five outings he is batting .188 with a double and two walks.
• Anthony Volpe is hitting .237 with 17 doubles, two triples, seven home runs and 25 walks.

Yankees Team Props

Guardians Recent Betting Performance

• The Guardians have played as underdogs in seven of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Guardians and their opponents are 5-5-0 when it comes to hitting the over.
• The Guardians have a record of 6-4-0 ATS over their last 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez paces the Guardians with 11 home runs and 29 runs batted in, while posting a team-best batting average of .327.
• Ramirez's home run total places him 33rd in the big leagues, and he ranks 74th in RBI.
• Ramirez brings a hitting streak of four games into this matchup. In his last five games he is hitting .368 with a double, two home runs, three walks and two RBIs.
• Steven Kwan is batting .312 with 13 doubles, five home runs and 20 walks.
• Kwan is 149th in home runs and 144th in RBI among all hitters in MLB.
• Carlos Santana paces the Guardians with 29 runs batted in.
• Kyle Manzardo leads the Guardians with 11 long balls and runs batted in, driving in 29.

Guardians Team Props

Guardians vs. Yankees Highlights | MLB on FOX

Check out the best moments between the Cleveland Guardians and the New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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