Yankees vs. Guardians Prediction, Odds, Picks - April 23

Aaron Judge and Jose Ramirez will be among the star attractions when the New York Yankees play the Cleveland Guardians on Wednesday at 1:10 p.m. ET, at Progressive Field. The Guardians are +142 moneyline underdogs for this matchup with the Yankees (-169). New York is the run-line favorite (-1.5). The over/under is 8.5 runs for this game.

Check out everything you need to know from a betting perspective on the Yankees-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Yankees vs. Guardians Highlights | MLB on FOX

Check out the best moments between the New York Yankees and the Cleveland Guardians.

Yankees vs. Guardians Game Information & Odds

• When: Wednesday, April 23, 2025 at 1:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and YES

Yankees vs. Guardians Prediction

• Score Prediction: Yankees 6, Guardians 5
• Total Prediction: Over 8.5 runs
• Win Probabilities: Yankees 52%, Guardians 48%

Yankees vs. Guardians Betting Insights

• The Yankees have entered the game as favorites 19 times this season and won 13, or 68.4%, of those games.
• This season New York has won four of its five games when favored by at least -169 on the moneyline.
• The implied probability of a win from the Yankees, based on the moneyline, is 62.8%.
• The Guardians have won in six, or 46.2%, of the 13 contests they have been named as odds-on underdogs this year.
• Cleveland has a win-loss record of 2-2 when favored by +142 or worse by oddsmakers this year.
• Sportsbooks have implied with the moneyline set for this matchup that the Guardians have a 41.3% chance of pulling out a win.

Yankees Recent Betting Performance

• The Yankees have a 5-2 record across the seven games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all had set totals), the Yankees combined with their opponents to go over the run total three times.
• The Yankees have a 4-6-0 record against the spread over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Judge has put up a team-high batting average of .411, while pacing the Yankees in home runs (seven) and runs batted in (25).
• Of all hitters in MLB, Judge ranks sixth in homers and first in RBI.
• Judge carries a four-game hitting streak into this matchup. In his last five games he is hitting .450 with two doubles, two walks and three RBI.
• Ben Rice is batting .286 with three doubles, a triple, six home runs and 10 walks.
• Rice is 16th in home runs and 96th in RBI among all major league batters this season.
• Paul Goldschmidt has five doubles, a home run and eight walks while hitting .371.
• Goldschmidt is on a seven-game hitting streak entering this contest. In his last 10 games he is hitting .389 with a double, five walks and two RBI.
• Anthony Volpe is batting .209 with five doubles, four home runs and 12 walks.

Yankees Team Props

Guardians Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by sportsbooks, the Guardians had a record of 4-3.
• In their last 10 games with a total, the Guardians and their opponents are 5-3-2 when it comes to hitting the over.
• Over their last 10 games, the Guardians are 6-4-0 against the spread.

Guardians Recent Stats

Guardians Player Insights

• Steven Kwan leads the team in batting average with a high-water mark of .341.
• Kwan's home run total puts him 45th in the big leagues, and he is 39th in RBI.
• Kwan brings a hitting streak of six games into this matchup. In his last 10 outings he is hitting .341 with two doubles, two home runs, four walks and six RBI.
• Ramirez is batting .263 with four doubles, five home runs and eight walks.
• Ramirez ranks 28th in home runs and 48th in RBI among all MLB hitters this year.
• Kyle Manzardo has been solid source of run production for the Guardians with seven long balls and 18 runs batted in.
• Gabriel Arias is hitting .271 with three doubles, four home runs and five walks.

Guardians Team Props

Yankees vs. Guardians Highlights | MLB on FOX

Check out the best moments between the New York Yankees and the Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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