Twins vs. White Sox Prediction, Odds, Picks - September 2

Lenyn Sosa and the Chicago White Sox will hit the field on Tuesday at Target Field against Simeon Woods Richardson, who starts for the Minnesota Twins. First pitch will be at 7:40 p.m. ET. The Twins are the favorite in this one, at -143, while the underdog White Sox have +120 odds to win. Minnesota is favored on the run line (-1.5). A 9.5-run over/under is listed for this contest.

Here's everything you need from a betting perspective on the Twins-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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White Sox vs. Twins Highlights | MLB on FOX

Check out the best moments between the Chicago White Sox and the Minnesota Twins.

Twins vs. White Sox Game Information & Odds

• When: Tuesday, September 2, 2025 at 7:40 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: MNNT and CHSN

Twins vs. White Sox Prediction

• Score Prediction: Twins 5, White Sox 4
• Total Prediction: Under 9.5 runs
• Win Probabilities: Twins 53%, White Sox 47%

Twins vs. White Sox Betting Insights

• The Twins have been favorites in 78 games this season and won 38 (48.7%) of those contests.
• Minnesota is 17-13 this season when entering a game favored by -143 or more on the moneyline.
• The implied probability of a win from the Twins, based on the moneyline, is 58.8%.
• The White Sox have been chosen as underdogs in 136 games this year and have walked away with the win 49 times (36%) in those games.
• Chicago has a mark of 35-70 in contests where sportsbooks favor it by +120 or worse on the moneyline.
• The moneyline set for this matchup implies the White Sox have a 45.5% chance of coming away with a victory in the contest.

Twins Recent Betting Performance

• The Twins have a 2-3 record across the five games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all 10 of them had set totals), the Twins and their opponents combined to go over the run total nine times.
• The Twins' ATS record is 5-5-0 over their past 10 games.

Twins Recent Stats

Twins Player Insights

• Byron Buxton paces the Twins with 29 home runs and 72 runs batted in, while racking up a team-best batting average of .272.
• Buxton's home runs place him 12th in the majors, and he is 49th in RBI.
• Buxton carries a five-game hitting streak into this matchup. During his last five outings he is batting .350 with two doubles, four home runs, two walks and 10 RBIs.
• Trevor Larnach is batting .252 with 19 doubles, a triple, 16 home runs and 45 walks.
• Larnach is 98th in homers and 112th in RBI in the majors.
• Larnach has three straight games with at least one hit. In his last five games he is batting .500 with two walks and three RBIs.
• Brooks Lee is hitting .244 with 13 doubles, a triple, 14 home runs and 26 walks.
• Lee is on a two-game hitting streak entering this contest. In his last five games he is hitting .150 with a home run, a walk and two RBIs.
• Ryan Jeffers has 24 doubles, nine home runs and 47 walks while hitting .258.

Twins Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and won five of those contests.
• In their last 10 games with a total, the White Sox and their opponents are 6-4-0 when it comes to hitting the over.
• The White Sox have a record of 6-4-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Andrew Benintendi is hitting .238 with 15 doubles, two triples, 15 home runs and 34 walks, while getting on base at a rate of .301.
• Benintendi ranks 113th in home runs and 146th in RBI among all hitters in the majors.
• Sosa has hit 18 home runs with 61 RBI while hitting .266. Those numbers are pace the clubhouse.
• Sosa is currently 76th in home runs and 83rd in RBI in the major leagues.
• Chase Meidroth is batting .253 with 14 doubles, four home runs and 38 walks.
• Mike Tauchman is hitting .275 with 15 doubles, a triple, eight home runs and 39 walks.

White Sox Team Props

White Sox vs. Twins Highlights | MLB on FOX

Check out the best moments between the Chicago White Sox and the Minnesota Twins.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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