Twins vs. White Sox Prediction, Odds, Picks - March 31

Updated Mar. 31, 2025 2:00 p.m. ET

Data Skrive

Willi Castro and the Minnesota Twins will meet Andrew Vaughn and the Chicago White Sox on Monday at Rate Field, at 2:10 p.m. ET. The Twins are the favorite in this one, at -190, while the underdog White Sox have +159 odds to upset. Minnesota is the favorite on the run line (-1.5 with -110 odds). A 7.5-run total has been set for this game.

Here's everything you need to know from a betting perspective on the Twins-White Sox game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Twins vs. Cardinals Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and the St. Louis Cardinals.

Twins vs. White Sox Game Information & Odds

When: Monday, March 31, 2025 at 2:10 p.m. ET
Where: Rate Field in Chicago, Illinois
How to watch on TV: CHSN and MNNT

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Twins	-190	+159	7.5	-111	-109	-1.5	-110	-109

Twins vs. White Sox Prediction

Score Prediction: White Sox 4, Twins 2
Total Prediction: Under 7.5 runs
Win Probabilities: Twins 66%, White Sox 34%

Twins vs. White Sox Betting Insights

The Twins put together a 63-50 record in games they were listed as the moneyline favorite last season (winning 55.8% of those games).
In games it played as a moneyline favorite with odds of -190 or shorter last year, Minnesota had a record of 18-4 (81.8%).
Based on this game's moneyline, the Twins have an implied win probability of 65.5%.
Last season, the White Sox won 37 out of the 154 games, or 24%, in which they were the underdog.

Twins Player Insights

Castro hit .247 last season with 12 home runs and 60 RBI.
Carlos Correa hit .310 with an OBP of .388 and a slugging percentage of .517.
Ryan Jeffers finished with a .226 average last season, with 21 home runs and 64 RBI.
Byron Buxton collected 99 hits, posted an OBP of .335 and a .524 SLG.

White Sox Player Insights

Vaughn had 70 runs batted in while putting up a batting average of .246 last season.
Andrew Benintendi hit 20 home runs on the season while slugging .396.
Luis Robert hit .224 a season ago with 19 doubles, 14 home runs and 28 walks.
Lenyn Sosa had 13 doubles, eight home runs and 12 walks while batting .254.