Twins vs. Cardinals Prediction, Odds, Picks - March 30

Updated Mar. 30, 2025 2:00 p.m. ET

Data Skrive

The Minnesota Twins and St. Louis Cardinals will meet on Sunday at Busch Stadium, at 2:15 p.m. ET, with Willi Castro and Alec Burleson among those expected to produce at the plate. The Twins are favored in this one, at -111, while the underdog Cardinals have -108 odds to play spoiler. Minnesota is a 1.5-run favorite (at +150 odds). The total for the contest is set at 8.5 runs.

Check out everything you need to know from a betting perspective on the Twins-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Cardinals Game Information & Odds

When: Sunday, March 30, 2025 at 2:15 p.m. ET
Where: Busch Stadium in St. Louis, Missouri
How to Watch on TV: FDSMW and MNNT

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Twins	-111	-108	8.5	-101	-120	-1.5	+150	-181

Twins vs. Cardinals Prediction

Score Prediction: Cardinals 6, Twins 2
Total Prediction: Under 8.5 runs
Win Probabilities: Twins 79%, Cardinals 21%

Twins vs. Cardinals Betting Insights

The Twins won 63 of the 113 games they were the moneyline favorite last season (55.8%).
In games it played as a moneyline favorite with odds of -111 or shorter last year, Minnesota finished with a record of 63-49 (56.2%).
The Twins have a 52.6% chance to win this matchup based on the moneyline's implied probability.
The Cardinals won 42, or 50.6%, of the 83 games they played as underdogs last season.

Twins Player Insights

Castro hit .247 last season with 12 home runs and 60 RBI.
Carlos Correa hit .310 with an OBP of .388 and a slugging percentage of .517.
Ryan Jeffers slugged 21 home runs and collected 64 RBI last season while batting .226.
Byron Buxton collected 99 hits, posted an OBP of .335 and a .524 SLG.

Cardinals Player Insights

Brendan Donovan put up 163 hits with a batting average of .278 last season.
Burleson had 21 home runs and 78 runs batted in a season ago.
Masyn Winn hit .267 a season ago with 32 doubles, five triples, 15 home runs and 41 walks.
Nolan Arenado had 23 doubles, 16 home runs and 44 walks while batting .272.