Tigers vs. Pirates Prediction, Odds, Picks - July 22

Tommy Pham and the Pittsburgh Pirates take the field on Tuesday at PNC Park against Casey Mize, who is starting for the Detroit Tigers. First pitch is at 6:40 p.m. ET for the second game of a three-game series. The Tigers are -135 moneyline favorites for this matchup with the Pirates (+114). Detroit is the favorite on the run line (-1.5). An 8-run over/under is set for the contest.

Take a look at everything you need to know from a betting perspective on the Tigers-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Tigers vs. Pirates Game Information & Odds

• When: Tuesday, July 22, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and FDSDET

Tigers vs. Pirates Prediction

• Score Prediction: Tigers 5, Pirates 4
• Total Prediction: Over 8 runs
• Win Probabilities: Tigers 51%, Pirates 49%

Tigers vs. Pirates Betting Insights

• The Tigers have won 45, or 67.2%, of the 67 games they've played as favorites this season.
• Detroit is 36-15 this season when entering a game favored by -135 or more on the moneyline.
• The sportsbooks' moneyline implies a 57.4% chance of a victory for the Tigers.
• The Pirates have been victorious in 26, or 37.7%, of the 69 contests they have been chosen as underdogs in this season.
• This season, Pittsburgh has been victorious 17 times in 51 chances when named as an underdog of at least +114 or longer on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 46.7% chance of walking away with the win.

Tigers Recent Betting Performance

• The Tigers went 2-4 over the six games they were moneyline favorites in their last 10 matchups.
• In their last 10 outings, the Tigers and their opponents combined to hit the over on the total four times (all 10 games had set totals).
• The Tigers' ATS record is 2-8-0 over their past 10 games.

Tigers Recent Stats

Tigers Player Insights

• Gleyber Torres paces the Tigers with a .281 batting average.
• Including all MLB hitters, Torres ranks 30th in batting average, fifth in on-base percentage, and 84th in slugging.
• Torres takes a hitting streak of two games into this game. In his last five games he is hitting .353 with three walks and an RBI.
• Riley Greene's 25 home runs and 79 runs batted in are both team-highs.
• Greene is eighth in homers and fifth in RBI among all hitters in the majors.
• Spencer Torkelson is batting .233 with 20 doubles, 21 home runs and 46 walks.
• Zach McKinstry is batting .276 with 14 doubles, eight triples, eight home runs and 36 walks.

Tigers Team Props

Pirates Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Pirates have a record of 1-5.
• When it comes to hitting the over, the Pirates and their opponents are 4-6-0 in their last 10 games with a total.
• The Pirates have won five of their last 10 games against the spread.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz paces the Pirates with 16 long balls.
• Among all hitters in the majors, Cruz's home run total is 47th and his RBI tally ranks 115th.
• Andrew McCutchen has a club-best .256 batting average.
• McCutchen ranks 157th among all hitters in the big leagues in home runs, and 179th in RBI.
• Bryan Reynolds has collected a team-best 48 runs batted in.
• Isiah Kiner-Falefa is hitting .274 with 12 doubles, two triples, a home run and 15 walks.

Pirates Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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