Tigers vs. Guardians AL Wild Card Game 1 Prediction, Odds, Picks - September 30

The AL Wild Card Series starts Tuesday at 1:08 p.m. ET when the Detroit Tigers visit the Cleveland Guardians live from Progressive Field, and airing on ESPN. The favored Tigers have -177 moneyline odds against the underdog Guardians, who are listed at +148. Detroit is a 1.5-run favorite (at +113 odds). The matchup's over/under is set at 6 runs.

Take a look at everything you need to know from a betting perspective on the Tigers-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Tigers vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Detroit Tigers and Cleveland Guardians.

Tigers vs. Guardians Game Information & Odds

• When: Tuesday, September 30, 2025 at 1:08 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: ESPN

Tigers vs. Guardians Prediction

• Score Prediction: Guardians 5, Tigers 4
• Total Prediction: Over 6 runs
• Win Probabilities: Tigers 53%, Guardians 47%

Tigers vs. Guardians Betting Insights

• The Tigers have entered the game as favorites 112 times this season and won 63, or 56.2%, of those games.
• This season Detroit has won 25 of its 41 games, or 61%, when favored by at least -177 on the moneyline.
• The moneyline for this contest implies a 63.9% chance of a victory for the Tigers.
• The Guardians have come away with 42 wins in the 87 contests they have been listed as the underdogs in this season.
• Cleveland has a mark of 5-9 in contests where sportsbooks favor it by +148 or worse on the moneyline.
• The moneyline set for this matchup implies the Guardians have a 40.3% chance of walking away with the win.

Tigers Recent Betting Performance

• In the last 10 games, the Tigers were favored on the moneyline six times, but they lost each matchup.
• Over their last 10 matchups, the Tigers and their opponents combined to go over the total three times (all 10 games had set totals).
• The Tigers have gone 1-9-0 against the spread over their past 10 games.

Tigers Recent Stats

Tigers Player Insights

• Gleyber Torres has 22 doubles, 16 home runs and 85 walks while batting .256.
• Of all batters in baseball, Torres' home run total places him 127th, and his RBI tally ranks him 73rd.
• Riley Greene has shown his power as he leads his team with 36 home runs and 111 runs batted in.
• Among all major league hitters, Greene ranks 10th in homers and seventh in RBI.
• Spencer Torkelson is batting .240 with 27 doubles, a triple, 31 home runs and 72 walks.
• Zach McKinstry has a club-leading .259 batting average.

Tigers Team Props

Guardians Recent Betting Performance

• Over the past 10 games, the Guardians have been underdogs twice and won both contests.
• When it comes to hitting the over, the Guardians and their opponents are 3-6-1 in their last 10 games with a total.
• Over their last 10 games, the Guardians are 5-5-0 against the spread.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez paces the Guardians with 30 home runs and 85 runs batted in, while recording a team-best batting average of .283.
• Ramirez's home run total puts him 30th in the majors, and he ranks 42nd in RBI.
• Steven Kwan has 29 doubles, a triple, 11 home runs and 55 walks while hitting .272.
• Kwan is currently 192nd in homers and 142nd in RBI in the big leagues.
• Kyle Manzardo is batting .234 with 19 doubles, two triples, 27 home runs and 48 walks.
• Angel Martinez is hitting .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Guardians Team Props

Tigers vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Detroit Tigers and Cleveland Guardians.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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