Reds vs. White Sox Prediction, Odds, Picks - May 14

Elly De La Cruz and the Cincinnati Reds will try to take down Luis Robert and the Chicago White Sox when the teams meet on Wednesday at 7:14 p.m. ET. The White Sox are listed as +167 moneyline underdogs in this matchup against the Reds (-201). Cincinnati is a 1.5-run favorite (at +100 odds). The total is 8.5 runs for this matchup (with -116 odds to hit the over and -104 odds to go under).

Check out everything you need from a betting perspective on the Reds-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Reds vs. White Sox Game Information & Odds

• When: Wednesday, May 14, 2025 at 7:14 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and CHSN

Reds vs. White Sox Prediction

• Score Prediction: Reds 5, White Sox 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Reds 55%, White Sox 45%

Reds vs. White Sox Betting Insights

• This season, the Reds have won 10 out of the 20 games, or 50%, in which they've been favored.
• This season Cincinnati has won two of its three games when favored by at least -201 on the moneyline.
• The moneyline for this contest implies a 66.8% chance of a victory for the Reds.
• The White Sox have been underdogs in 42 games this season and have come away with the win 13 times (31%) in those contests.
• This year, Chicago has won five of 21 games when listed as at least +167 or worse on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the White Sox have a 37.5% chance of pulling out a win.

Reds Recent Betting Performance

• The Reds were the moneyline favorite three times over the last 10 games, but they lost each matchup.
• In their last 10 matchups -- all had a set run total -- the Reds and their opponents combined to hit the over on the total three times.
• The Reds' ATS record is 3-7-0 over their past 10 games.

Reds Recent Stats

Reds Player Insights

• De La Cruz has accumulated a team-high seven home runs and 30 runs batted in.
• Of all hitters in baseball, De La Cruz's home run total ranks him 44th, and his RBI tally puts him 13th.
• TJ Friedl is batting .274 with six doubles, a triple, three home runs and 20 walks.
• Friedl ranks 158th in homers in baseball, and 114th in RBI.
• Gavin Lux has put up a team-best batting average of .276.
• Jose Trevino is batting .307 with 10 doubles, three home runs and five walks.

Reds Team Props

White Sox Recent Betting Performance

• In 10 games as underdogs over the last 10 matchups, the White Sox have a record of 4-6.
• When it comes to hitting the over, the White Sox and their opponents are 3-6-1 in their last 10 games with a total.
• The White Sox have won six of their last 10 games against the spread.

White Sox Recent Stats

White Sox Player Insights

• Miguel Vargas is hitting .221 with nine doubles, three home runs and 17 walks, while getting on base at a rate of .314.
• Vargas' home run total places him 158th in the majors, and he is 144th in RBI.
• Robert has racked up a team-high five home runs.
• Robert ranks 88th among all hitters in the majors in home runs, and 131st in RBI.
• Andrew Vaughn leads the White Sox in home runs (five) and runs batted in (17).
• Matthew Thaiss has four doubles, a home run and 19 walks while hitting .224.

White Sox Team Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cincinnati Reds

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