Reds vs. Nationals Prediction, Odds, Picks - May 3

Elly De La Cruz and the Cincinnati Reds square off against James Wood and the Washington Nationals on Saturday at 6:40 p.m. ET. The Reds are the favorite in this one, at -192, while the underdog Nationals have +159 odds to win. Cincinnati is the run-line favorite (-1.5). The over/under is 8.5 runs for the matchup.

Check out everything you need to know from a betting perspective on the Reds-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Nationals vs. Reds Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Cincinnati Reds.

Reds vs. Nationals Game Information & Odds

• When: Saturday, May 3, 2025 at 6:40 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and MASN

Reds vs. Nationals Prediction

• Score Prediction: Reds 4, Nationals 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Reds 60%, Nationals 40%

Reds vs. Nationals Betting Insights

• The Reds have won 10, or 58.8%, of the 17 games they've played as favorites this season.
• Cincinnati has played as favorites of -192 or more twice this season and won both games.
• The moneyline for this contest implies a 65.8% chance of a victory for the Reds.
• The Nationals have won in 12, or 44.4%, of the 27 contests they have been named as odds-on underdogs this year.
• Washington has yet to win this season when listed as an underdog of +159 or worse on the moneyline this season.
• The Nationals have an implied victory probability of 38.6% according to the moneyline set by oddsmakers for this matchup.

Reds Recent Betting Performance

• The Reds went 6-3 over the nine games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings -- all had a set run total -- the Reds and their opponents combined to hit the over on the total three times.
• The Reds have put together a 6-4-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• The Reds' best power option comes in the form of De La Cruz and his five-home-run 24-RBI season, both team highs.
• De La Cruz's home runs rank him 53rd in MLB, and he ranks 13th in RBI.
• TJ Friedl has six doubles, a triple, a home run and 11 walks while hitting .273.
• Friedl ranks 224th in homers and 115th in RBI among all MLB hitters this year.
• Friedl heads into this game looking for his third game in a row with a hit. During his last five outings he is hitting .158 with two walks and an RBI.
• Gavin Lux paces the Reds with a team-high batting average of .317.
• Noelvi Marte is hitting .306 with four doubles, a triple, three home runs and five walks.

Reds Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in nine of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Nationals and their opponents have combined to hit the over four times.
• The Nationals have won six of their last 10 games against the spread.

Nationals Recent Stats

Nationals Player Insights

• Wood paces the Nationals with nine long balls.
• Among all batters in the big leagues, Wood is fifth in home runs and 24th in RBI.
• Nathaniel Lowe has collected 25 runs batted in to lead his team.
• Lowe is 34th in home runs and 10th in RBI among all major league hitters this year.
• Luis Garcia is hitting .243 with five doubles, two home runs and eight walks.
• Keibert Ruiz paces the Nationals with a team-leading batting average of .291.

Nationals Team Props

Nationals vs. Reds Highlights | MLB on FOX

Check out the best moments between the Washington Nationals and the Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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