Reds vs. Giants Prediction, Odds, Picks - March 29

Justin Verlander will aim to shut down Spencer Steer and company when the San Francisco Giants play the Cincinnati Reds on Saturday at 4:10 p.m. ET, at Great American Ball Park. The Reds are the favorite in this one, at -122, while the underdog Giants have +102 odds to play spoiler. Cincinnati is favored on the run line (-1.5). The total is 8.5 runs for the contest (with -115 odds on the over and -105 odds on the under).

Take a look at everything you need to know from a betting perspective on the Reds-Giants game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Giants vs. Reds Highlights | MLB on FOX

Check out the top highlights between the San Francisco Giants and the Cincinnati Reds on Opening Day.

Reds vs. Giants Game Information & Odds

• When: Saturday, March 29, 2025 at 4:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: FDSOH and NBCS-BA

Reds vs. Giants Prediction

• Score Prediction: Giants 6, Reds 5
• Total Prediction: Over 8.5 runs
• Win Probabilities: Reds 55%, Giants 45%

Reds vs. Giants Betting Insights

• The Reds won 53.7% of the games last season they were the moneyline favorite (36-31).
• In games it played as a moneyline favorite with odds of -122 or shorter last year, Cincinnati finished with a record of 28-24 (53.8%).
• The Reds have an implied moneyline win probability of 55% in this matchup.
• Last season, the Giants were the underdog 78 times and won 33, or 42.3%, of those games.

Reds Player Insights

• Elly De La Cruz hit 25 home runs last season while also driving in 76 runs.
• Steer was a key run producer with a .225 average, 20 homers and 92 RBI.
• Gavin Lux finished last season with 10 home runs, 50 RBI and a batting average of .251.
• Jeimer Candelario collected 96 hits, posted an OBP of .279 and a .429 SLG.

Reds Team Props

Giants Player Insights

• Willy Adames had 32 home runs and 112 runs batted in last season.
• Matt Chapman hit .247 with 39 doubles, two triples, 27 home runs and 64 walks.
• Heliot Ramos had a batting average of .269 with 128 total hits last season.
• Mike Yastrzemski had 16 doubles, nine triples, 18 home runs and 38 walks while hitting .231.

Giants Team Props

Giants vs. Reds Highlights | MLB on FOX

Check out the top highlights between the San Francisco Giants and the Cincinnati Reds on Opening Day.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Cincinnati Reds

San Francisco Giants