Red Sox vs. Orioles Prediction, Odds, Picks - August 26

Trevor Story and the Boston Red Sox take on Jeremiah Jackson and the Baltimore Orioles at Oriole Park at Camden Yards on Tuesday, at 6:35 p.m. ET. The Red Sox are the favorite in this one, at -119, while the underdog Orioles have -101 odds to win. Boston is favored on the run line (-1.5 with +137 odds). An 8.5-run total is set in the contest.

Take a look at everything you need to know from a betting perspective on the Red Sox-Orioles game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

Red Sox vs. Orioles Game Information & Odds

• When: Tuesday, August 26, 2025 at 6:35 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and NESN

Red Sox vs. Orioles Prediction

• Score Prediction: Red Sox 5, Orioles 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Red Sox 53%, Orioles 47%

Red Sox vs. Orioles Betting Insights

• The Red Sox have been favorites in 78 games this season and won 46 (59%) of those contests.
• Boston is 40-25 this season when entering a game favored by -119 or more on the moneyline.
• The Red Sox have a 54.3% chance to win this game based on the implied probability of the moneyline.
• The Orioles have been chosen as underdogs in 69 games this year and have walked away with the win 32 times (46.4%) in those games.
• This season, Baltimore has been victorious 27 times in 57 chances when named as an underdog of at least -101 or longer on the moneyline.
• The Orioles have an implied victory probability of 50.2% according to the moneyline set for this matchup.

Red Sox Recent Betting Performance

• The Red Sox were the moneyline favorite in seven of their last 10 games, and they went 4-3 in those matchups.
• Over their last 10 matchups (all had set totals), the Red Sox combined with their opponents to hit the over on the total five times.
• The Red Sox's ATS record is 4-6-0 over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran is the Red Sox best hitter thus far this season, hitting at a team-leading .258 clip along with 13 homers and 73 RBI.
• Duran is 131st in homers and 34th in RBI among all hitters in baseball.
• Story has 82 runs batted in while hitting .258. Both pace his team.
• Story ranks 53rd in homers and 17th in RBI among all batters in MLB.
• Alex Bregman has 24 doubles, 16 home runs and 39 walks while batting .301.
• Ceddanne Rafaela has 27 doubles, three triples, 14 home runs and 22 walks while hitting .247.

Red Sox Team Props

Orioles Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by sportsbooks, the Orioles had a record of 4-3.
• In their last 10 games with a total, the Orioles and their opponents have failed to hit the over four times.
• The Orioles have six wins against the spread in their last 10 chances.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson leads the lineup with a batting average of .283, while leading the Orioles in home runs, with 16 and runs batted in with 59.
• Among all hitters in the big leagues, Henderson's home run total ranks 89th and his RBI tally ranks 78th.
• Henderson brings a hitting streak of seven games into this matchup. During his last 10 outings he is hitting .282 with a double, a triple, two home runs, six walks and eight RBIs.
• Jackson Holliday is hitting .244 with 17 doubles, two triples, 15 home runs and 37 walks.
• Holliday is 106th overall in homers and 130th in RBI this season.
• Colton Cowser is batting .225 with 11 doubles, 12 home runs and 16 walks.
• Ryan Mountcastle has 14 doubles, four home runs and 11 walks while batting .256.

Orioles Team Props

Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Baltimore Orioles

Boston Red Sox