Rays vs. Red Sox Prediction, Odds, Picks - September 20

The Boston Red Sox will look to Trevor Story for continued offensive production when they take on Yandy Diaz and the Tampa Bay Rays on Saturday, in the second game of a three-game series at George M. Steinbrenner Field. The Rays are the favorite in this one, at -112, while the underdog Red Sox have -107 odds to upset. Boston is the run-line favorite (-1.5). The over/under is 8 runs for this game (with -105 odds on the over and -116 odds on the under).

Take a look at everything you need to know from a betting perspective on the Rays-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Rays Highlights | MLB on FOX

Check out the best highlights between the Boston Red Sox and the Tampa Bay Rays.

Rays vs. Red Sox Game Information & Odds

• When: Saturday, September 20, 2025 at 7:05 p.m. ET
• Where: George M. Steinbrenner Field in Tampa, Florida
• How to watch on TV: FDSSUN and NESN

Rays vs. Red Sox Prediction

• Score Prediction: Rays 5, Red Sox 4
• Total Prediction: Under 8 runs
• Win Probabilities: Rays 51%, Red Sox 49%

Rays vs. Red Sox Betting Insights

• This season, the Rays have won 44 out of the 77 games, or 57.1%, in which they've been favored.
• Tampa Bay has a record of 41-29 in games when oddsmakers favor them by at least -112 on the moneyline.
• The implied probability of a win from the Rays, based on the moneyline, is 52.8%.
• The Red Sox have been victorious in 26, or 48.1%, of the 54 contests they have been chosen as underdogs in this season.
• Boston has a mark of 24-25 in contests where oddsmakers favor it by -107 or worse on the moneyline.
• The moneyline set for this matchup implies the Red Sox have a 51.7% chance of walking away with the win.

Rays Recent Betting Performance

• The Rays were favored on the moneyline in four of their last 10 games, and they went 1-3 in those matchups.
• In their last 10 outings, the Rays and their opponents combined to go over the run total five times (all 10 of the games had set totals).
• The Rays' record against the spread is 5-5-0 over their past 10 games.

Rays Recent Stats

Rays Player Insights

• Junior Caminero paces the Rays in home runs (44) and runs batted in (108).
• Among all hitters in baseball, Caminero is sixth in homers and fifth in RBI.
• Diaz has a club-best .300 batting average.
• Diaz is 45th in home runs and 34th in RBI among all major league hitters this season.
• Brandon Lowe is hitting .258 with 18 doubles, 29 home runs and 36 walks.
• Lowe will look to build on his two-game hitting in this game. In his last five games he is batting .217 with a double, a home run and six RBIs.
• Chandler Simpson is hitting .301 with 14 doubles, three triples and 20 walks.
• Simpson brings a four-game streak with at least one hit into this one. In his last five games he is hitting .444 with three doubles, a walk and three RBIs.

Rays Team Props

Red Sox Recent Betting Performance

• The Red Sox have played as underdogs in three of their past 10 games and have gone 1-2 in those contests.
• In their last 10 games with a total, the Red Sox and their opponents are 2-7-1 when it comes to hitting the over.
• The Red Sox have four wins against the spread in their last 10 chances.

Red Sox Recent Stats

Red Sox Player Insights

• Jarren Duran is hitting .261 with 39 doubles, 13 triples, 16 home runs and 57 walks, while getting on base at a rate of .335.
• Duran ranks 120th in home runs and 34th in RBI among all batters in MLB.
• Story proven to be a run producer as he leads his team with 25 home runs and 94 runs batted in, with a team-leading .265 batting average.
• Among all MLB hitters, Story ranks 45th in home runs and 18th in RBI.
• Alex Bregman has 27 doubles, 18 home runs and 47 walks while hitting .273.
• Ceddanne Rafaela is batting .243 with 30 doubles, three triples, 16 home runs and 25 walks.

Red Sox Team Props

Red Sox vs. Rays Highlights | MLB on FOX

Check out the best highlights between the Boston Red Sox and the Tampa Bay Rays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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