Pirates vs. Cubs Prediction, Odds, Picks - May 1

Oneil Cruz and the Pittsburgh Pirates will play Kyle Tucker and the Chicago Cubs on Thursday at PNC Park, at 12:35 p.m. ET. The Pirates are -127 moneyline favorites in this matchup with the Cubs (+107). Pittsburgh is the favorite on the run line (-1.5 with +167 odds). The over/under for the game is listed at 8 runs.

Take a look at everything you need from a betting perspective on the Pirates-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and the Pittsburgh Pirates.

Pirates vs. Cubs Game Information & Odds

• When: Thursday, May 1, 2025 at 12:35 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and MARQ

Pirates vs. Cubs Prediction

• Score Prediction: Cubs 4, Pirates 3
• Total Prediction: Under 8 runs
• Win Probabilities: Pirates 57%, Cubs 43%

Pirates vs. Cubs Betting Insights

• The Pirates have been favorites in 11 games this season and won five (45.5%) of those contests.
• Pittsburgh has entered six games this season favored by -127 or more and is 3-3 in those contests.
• The Pirates have a 55.9% chance to win this game based on the implied probability of the moneyline.
• The Cubs have won in seven, or 46.7%, of the 15 contests they have been named as odds-on underdogs this year.
• Chicago has a win-loss record of 2-5 when favored by +107 or worse by sportsbooks this year.
• The moneyline set for this matchup implies the Cubs have a 48.3% chance of walking away with the win.

Pirates Recent Betting Performance

• The Pirates have been listed as the moneyline favorite by bookmakers just two times over the last 10 games, and lost both matchups.
• Over their last 10 outings (all 10 of them had set totals), the Pirates and their opponents combined to hit the over five times.
• The Pirates' ATS record is 6-4-0 over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• The Pirates' best power option comes in the form of Cruz and his eight-dinger 16-RBI season, both team highs.
• Including all MLB hitters, Cruz ranks 75th in batting average, 39th in on-base percentage, and 19th in slugging.
• Andrew McCutchen has six doubles, three home runs and 12 walks while hitting .277.
• McCutchen has three games in a row with at least one hit. During his last five outings he is hitting .368 with two doubles, a home run, two walks and three RBI.
• Enmanuel Valdez has three doubles, two triples, two home runs and 10 walks while batting .227.
• Valdez has at least one base hit in two straight games. In his last five games he is batting .250 with a home run, a walk and two RBI.
• Isiah Kiner-Falefa has a club-leading .280 batting average.

Pirates Team Props

Cubs Recent Betting Performance

• In three games as underdogs over the last 10 matchups, the Cubs have a record of 2-1.
• In their last 10 games with a total, the Cubs and their opponents have failed to hit the over four times.
• The Cubs are 5-5-0 ATS over their last 10 games.

Cubs Recent Stats

Cubs Player Insights

• Tucker paces the Cubs with seven home runs and runs batted in, driving in 27.
• Among all hitters in the big leagues, Tucker is 20th in homers and fifth in RBI.
• Pete Crow-Armstrong has 10 doubles, a triple, six home runs and six walks while batting .275.
• Crow-Armstrong is 31st among all hitters in the big leagues in homers, and 19th in RBI.
• Carson Kelly has seven home runs, tops in the clubhouse.
• Seiya Suzuki has swatted a team-high seven home runs.

Cubs Team Props

Cubs vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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