Pirates vs. Brewers Prediction, Odds, Picks - May 23

Rhys Hoskins and the Milwaukee Brewers take the field on Friday at PNC Park against Paul Skenes, who will start for the Pittsburgh Pirates. First pitch is at 6:40 p.m. ET. The Pirates are listed as -126 moneyline favorites in this matchup against the Brewers (+107). Pittsburgh is a 1.5-run favorite (at +178 odds). A 7-run over/under has been listed in this matchup.

Here's everything you need to know from a betting perspective on the Pirates-Brewers game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Brewers Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Milwaukee Brewers.

Pirates vs. Brewers Game Information & Odds

• When: Friday, May 23, 2025 at 6:40 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and FDSWI

Pirates vs. Brewers Prediction

• Score Prediction: Brewers 5, Pirates 4
• Total Prediction: Over 7 runs
• Win Probabilities: Pirates 50%, Brewers 50%

Pirates vs. Brewers Betting Insights

• The Pirates have won five, or 31.2%, of the 16 games they've played as favorites this season.
• Pittsburgh has entered eight games this season favored by -126 or more and is 3-5 in those contests.
• The moneyline for this contest implies a 55.8% chance of a victory for the Pirates.
• The Brewers have been underdogs in 25 games this season and have come away with the win seven times (28%) in those contests.
• This year, Milwaukee has won three of 15 games when listed as at least +107 or worse on the moneyline.
• The moneyline set for this matchup implies the Brewers have a 48.3% chance of coming away with a victory in the contest.

Pirates Recent Betting Performance

• The Pirates have been listed as the moneyline favorite by oddsmakers only one time over the last 10 games, and lost that matchup.
• Over their last 10 matchups (all 10 of them had set totals), the Pirates and their opponents combined to hit the over two times.
• The Pirates are 5-5-0 against the spread over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz paces the Pirates with eight home runs.
• Among all batters in baseball, Cruz ranks 47th in homers and 121st in RBI.
• Cruz carries a two-game hitting streak into this matchup. During his last five outings he is hitting .118 with a double, four walks and an RBI.
• Andrew McCutchen has seven doubles, three home runs and 23 walks while hitting .246.
• Of all MLB hitters, McCutchen ranks 180th in home runs and 191st in RBI.
• McCutchen heads into this game looking for his third game in a row with a hit. In his last five games he is batting .188 with four walks.
• Bryan Reynolds has accumulated a team-high 25 runs batted in.
• Isiah Kiner-Falefa is batting .282 with five doubles, a triple, a home run and nine walks.
• Kiner-Falefa brings a five-game streak with at least one hit into this one. During his last five outings he is batting .333 with two doubles and a walk.

Pirates Team Props

Brewers Recent Betting Performance

• The Brewers have played as underdogs in four of their past 10 games and won one of those contests.
• The Brewers and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Brewers have five wins against the spread in their last 10 chances.

Brewers Recent Stats

Brewers Player Insights

• William Contreras is batting .255 with six doubles, four home runs and 31 walks, while getting on base at a rate of .371.
• Contreras' home run total puts him 149th in the big leagues, and he is 84th in RBI.
• Jackson Chourio is hitting .245 with 15 doubles, a triple, seven home runs and six walks.
• Chourio ranks 70th among all hitters in MLB in home runs, and 59th in RBI.
• Brice Turang is batting .280 with four doubles, four home runs and 21 walks.
• Sal Frelick is batting .280 with five doubles, three triples, three home runs and 17 walks.

Brewers Team Props

Orioles vs. Brewers Highlights | MLB on FOX

Check out the best moments between the Baltimore Orioles and the Milwaukee Brewers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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