Phillies vs. Pirates Prediction, Odds, Picks - May 16

Ranger Suarez takes the mound for the Philadelphia Phillies on Friday at Citizens Bank Park against Jared Triolo and the Pittsburgh Pirates. First pitch is at 6:45 p.m. ET. The Pirates are +202 moneyline underdogs in this matchup against the Phillies (-247). Philadelphia is favored on the run line (-1.5 with -115 odds). A 9-run over/under is set in the game.

Here is everything you need to know from a betting perspective on the Phillies-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Phillies vs. Pirates Game Information & Odds

• When: Friday, May 16, 2025 at 6:45 p.m. ET
• Where: Citizens Bank Park in Philadelphia, Pennsylvania
• How to watch on TV: NBCS-PH and SportsNet PT

Phillies vs. Pirates Prediction

• Score Prediction: Phillies 6, Pirates 4
• Total Prediction: Over 9 runs
• Win Probabilities: Phillies 57%, Pirates 43%

Phillies vs. Pirates Betting Insights

• This season, the Phillies have won 21 out of the 35 games, or 60%, in which they've been favored.
• Philadelphia has entered four games this season favored by -247 or more and is 3-1 in those contests.
• The moneyline for this contest implies a 71.2% chance of a victory for the Phillies.
• The Pirates have come away with 10 wins in the 29 contests they have been listed as the underdogs in this season.
• This year, Pittsburgh has won one of four games when listed as at least +202 or worse on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 33.1% chance of coming away with a victory in the contest.

Phillies Recent Betting Performance

• The Phillies were the moneyline favorite for each of their last 10 games, and they went 6-4 in those matchups.
• Over their last 10 matchups, the Phillies and their opponents combined to hit the over four times (all 10 of the games had set totals).
• The Phillies' record against the spread is 4-6-0 over their past 10 games.

Phillies Recent Stats

Phillies Player Insights

• Kyle Schwarber has gone yard 15 times in the 2025 campaign while driving in 33 runs, both totals that lead the Phillies.
• Among all MLB hitters, Schwarber is 70th in batting average, 15th in on-base percentage, and eighth in slugging.
• Bryce Harper has nine doubles, seven home runs and 31 walks while batting .236.
• Harper ranks 48th in homers and 58th in RBI in the majors.
• Trea Turner leads the Phillies with a team-best batting average of .299.
• Bryson Stott is hitting .258 with five doubles, two triples, three home runs and 15 walks.
• Stott is riding a two-game hitting streak into this one. In his last five games he is hitting .167 with two walks and an RBI.

Phillies Team Props

Pirates Recent Betting Performance

• In eight games as underdogs over the last 10 matchups, the Pirates have a record of 3-5.
• When it comes to hitting the over, the Pirates and their opponents are 1-8-1 in their last 10 games with a total.
• The Pirates have won six of their last 10 games against the spread.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz paces the Pirates with eight long balls.
• Among all hitters in MLB, Cruz's home run total ranks 33rd and his RBI tally ranks 106th.
• Andrew McCutchen is hitting .254 with seven doubles, three home runs and 18 walks.
• McCutchen is 165th in home runs and 163rd in RBI among all major league hitters this season.
• Ke'Bryan Hayes is hitting .260 with three doubles, two triples, a home run and nine walks.
• Isiah Kiner-Falefa is hitting .283 with three doubles, a triple, a home run and seven walks.

Pirates Team Props

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Check out the best moments between the Pittsburgh Pirates and the New York Mets.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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