Padres vs. Reds Prediction, Odds, Picks - May 22

Updated May. 22, 2024 6:00 p.m. ET

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Jurickson Profar and the San Diego Padres face Elly De La Cruz and the Cincinnati Reds at Great American Ball Park on Wednesday. First pitch is at 6:40 PM ET. The favored Padres have -128 moneyline odds against the underdog Reds, who are listed at +108. San Diego is favored on the run line (-1.5 with +123 odds). The contest's over/under is set at 9.5 runs.

Here's everything you need to know from a betting perspective on the Padres-Reds game, regarding the run line, moneyline and total, plus expert picks.

Padres vs. Reds Highlights | MLB on FOX

Check out the greatest plays in this matchup between the San Diego Padres and the Cincinnati Reds.

Padres vs. Reds Game Information & Odds

• When: Wednesday, May 22, 2024 at 6:40 PM ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to Watch on TV: BSOH

Padres vs. Reds Prediction

• Score Prediction: Reds 6, Padres 5
• Total Prediction: Over 9.5 runs
• Win Probabilities: Padres 52%, Reds 48%

Padres vs. Reds Betting Insights

• The Padres have been favorites in 29 games this season and won 14 (48.3%) of those contests.
• San Diego has entered 19 games this season favored by -128 or more and is 9-10 in those contests.
• The Padres have a 56.1% chance to win this game based on the implied probability of the moneyline.
• The Reds have been chosen as underdogs in 27 games this year and have walked away with the win nine times (33.3%) in those games.
• Cincinnati has a win-loss record of 5-14 when favored by +108 or worse by sportsbooks this year.
• The Reds have an implied victory probability of 48.1% according to the moneyline set by sportsbooks for this matchup.

FINAL

SD 7 · CIN 3

MLB

RUN LINE

TO WIN

TOTAL

San Diego Padres

SD

-1.5

-127

o9.5

Cincinnati Reds

CIN

+1.5

+107

u9.5

Padres Recent Betting Performance

• The Padres went 1-4 over the five games they were a moneyline favorite in their last 10 matchups.
• In their last 10 matchups, the Padres and their opponents combined to hit the over five times (all 10 of the games had set totals).
• The Padres' record against the spread is 4-6-0 over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Profar leads the Padres with a team-high batting average of .339.
• In all of the majors, Profar ranks 46th in homers and 22nd in RBI.
• Profar has collected a hit in 10 straight games. In his last 10 outings he is batting .400 with a double, a home run, seven walks and four RBI.
• Jake Cronenworth's eight home runs and 32 runs batted in both pace his team.
• Cronenworth ranks 38th in homers in MLB, and 17th in RBI.
• Fernando Tatis Jr. has a team-high eight home runs.
• Luis Arraez is hitting .318 with 11 doubles, a triple and 11 walks.
• Arraez brings a six-game streak with at least one hit into this one. In his last 10 outings he is batting .341 with two doubles, two walks and three RBI.

Padres Team Props

Learn more about this Padres vs. Reds matchup on Fox Sports.

Reds Recent Betting Performance

• The Reds have played as underdogs in nine of their past 10 games and have gone 3-6 in those contests.
• In their last 10 games with a total, the Reds and their opponents have failed to hit the over six times.
• Over their last 10 games, the Reds are 7-3-0 against the spread.

Reds Recent Stats

Reds Player Insights

• De La Cruz paces the Reds with nine home runs and has accumulated a team-high batting average of .262.
• De La Cruz is 22nd in home runs and 62nd in RBI among all hitters in the big leagues.
• Spencer Steer has made the most of his opportunities as he leads his team with 31 RBI.
• Steer is currently 140th in home runs and 22nd in RBI in the big leagues.
• Tyler Stephenson is hitting .263 with seven doubles, five home runs and 13 walks.
• Jonathan India is hitting .216 with three doubles, a triple, two home runs and 23 walks.

Reds Team Props

Padres vs. Reds Highlights | MLB on FOX

Check out the greatest plays in this matchup between the San Diego Padres and the Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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MLB - San Diego Padres vs. Cincinnati Reds - 05/22/2024