Orioles vs. White Sox Prediction, Odds, Picks - June 1

Ryan O'Hearn and the Baltimore Orioles will look to outdo Miguel Vargas and the Chicago White Sox at Oriole Park at Camden Yards on Sunday at 1:35 p.m. ET. The Orioles are favored in this one, at -146, while the underdog White Sox have +123 odds to play spoiler. Baltimore is the favorite on the run line (-1.5 with +138 odds). The matchup's total is set at 9 runs.

Take a look at everything you need from a betting perspective on the Orioles-White Sox game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

White Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Chicago White Sox and the Baltimore Orioles!

Orioles vs. White Sox Game Information & Odds

• When: Sunday, June 1, 2025 at 1:35 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and CHSN

Orioles vs. White Sox Prediction

• Score Prediction: Orioles 7, White Sox 6
• Total Prediction: Over 9 runs
• Win Probabilities: Orioles 52%, White Sox 48%

Orioles vs. White Sox Betting Insights

• The Orioles have entered the game as favorites 31 times this season and won 11, or 35.5%, of those games.
• Baltimore has a record of 4-5 in games when sportsbooks favor them by at least -146 on the moneyline.
• The bookmakers' moneyline implies a 59.3% chance of a victory for the Orioles.
• The White Sox have been chosen as underdogs in 58 games this year and have walked away with the win 18 times (31%) in those games.
• This year, Chicago has won 17 of 53 games when listed as at least +123 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 44.8% chance of pulling out a win.

Orioles Recent Betting Performance

• The Orioles have a 2-1 record from the three games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups, the Orioles and their opponents combined to go over the run total five times (all 10 of the games had set totals).
• The Orioles have put together a 5-5-0 record against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• O'Hearn is the Orioles best hitter thus far this season, hitting at a team-leading .333 rate along with nine homers and 21 RBI.
• Including all MLB batters, O'Hearn is sixth in batting average, fifth in on-base percentage, and 12th in slugging.
• O'Hearn takes a hitting streak of 10 games into this matchup. During his last 10 outings he is hitting .475 with three doubles, two home runs, four walks and seven RBIs.
• Jackson Holliday is hitting .270 with seven doubles, two triples, seven home runs and 10 walks.
• Including all major league hitters, Holliday ranks 86th in home runs and 93rd in RBI.
• Gunnar Henderson is batting .254 with 11 doubles, two triples, seven home runs and 18 walks.
• Adley Rutschman is batting .203 with seven doubles, a triple, five home runs and 25 walks.

Orioles Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and won four of those contests.
• When it comes to hitting the over, the White Sox and their opponents are 5-5-0 in their last 10 games with a total.
• The White Sox have eight wins against the spread in their last 10 chances.

White Sox Recent Stats

White Sox Player Insights

• Vargas has put up a team-high eight home runs and has driven in 26 runs.
• Vargas is 65th in homers and 84th in RBI among all hitters in the majors.
• Luis Robert is batting .182 with six doubles, five home runs and 23 walks.
• Robert is 137th among all hitters in the big leagues in homers, and 146th in RBI.
• Andrew Benintendi has two doubles, a triple, six home runs and 12 walks while hitting .237.
• Chase Meidroth is batting .274 with four doubles, a home run and 16 walks.

White Sox Team Props

White Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Chicago White Sox and the Baltimore Orioles!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Baltimore Orioles

Chicago White Sox