Orioles vs. Royals Prediction, Odds, Picks - May 4

Cedric Mullins and the Baltimore Orioles will meet Maikel Garcia and the Kansas City Royals on Sunday at Oriole Park at Camden Yards, at 1:35 p.m. ET. The Orioles are -138 moneyline favorites in this matchup against the Royals (+117). Baltimore is the favorite on the run line (-1.5 with +150 odds). The game's over/under is listed at 9.5 runs.

Here is everything you need from a betting perspective on the Orioles-Royals game, regarding the run line, moneyline and total, plus expert picks.

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Royals' Cavan Biggio hits HR to extend lead against Orioles

Cavan Biggio hits HR that extended Kansas City Royals' 2-0 lead against the Baltimore Orioles.

Orioles vs. Royals Game Information & Odds

• When: Sunday, May 4, 2025 at 1:35 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MLB Network, MASN, and FDSKC

Orioles vs. Royals Prediction

• Score Prediction: Royals 10, Orioles 9
• Total Prediction: Over 9.5 runs
• Win Probabilities: Orioles 50%, Royals 50%

Orioles vs. Royals Betting Insights

• This season, the Orioles have been favored 18 times and won seven, or 38.9%, of those games.
• Baltimore has entered six games this season favored by -138 or more and is 2-4 in those contests.
• The implied probability of a win from the Orioles, based on the moneyline, is 58%.
• The Royals have been underdogs in 21 games this season and have come away with the win nine times (42.9%) in those contests.
• Kansas City has a win-loss record of 5-6 when favored by +117 or worse by sportsbooks this year.
• The moneyline set for this matchup implies the Royals have a 46.1% chance of coming away with a victory in the contest.

Orioles Recent Betting Performance

• The Orioles went 2-3 over the five games they were moneyline favorites in their last 10 matchups.
• Over their last 10 outings, the Orioles and their opponents combined to go over the run total one time (all 10 games had set totals).
• The Orioles have gone 4-6-0 against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Mullins leads the Orioles in home runs (six), runs batted in (20) and has a team-high batting average of .257.
• In all of MLB, Mullins is 36th in home runs and 34th in RBI.
• Ryan O'Hearn has hit six home runs to lead his team.
• O'Hearn has two games in a row with at least one hit. In his last five games he is hitting .235 with two home runs, three walks and five RBI.
• Adley Rutschman is batting .217 with three doubles, four home runs and 17 walks.
• Gunnar Henderson is hitting .250 with six doubles, a triple, three home runs and five walks.
• Henderson has recorded at least one hit in eight straight games. In his last 10 games he is hitting .308 with two doubles, a home run, two walks and two RBI.

Orioles Team Props

Royals Recent Betting Performance

• The Royals have played as underdogs in eight of their past 10 games and won six of those contests.
• In their last 10 games with a total, the Royals and their opponents have failed to hit the over seven times.
• The Royals are 8-2-0 ATS over their last 10 games.

Royals Recent Stats

Royals Player Insights

• Bobby Witt Jr. has 12 doubles, three home runs and 14 walks while batting .302.
• In all of the big leagues, Witt is 123rd in home runs and 75th in RBI.
• Garcia's .307 batting average paces his team.
• Garcia is 173rd overall in home runs and 139th in RBI this season.
• Vinnie Pasquantino has been solid source of run production for the Royals with five long balls and 21 runs batted in.
• Salvador Perez is hitting .237 with 11 doubles, two home runs and seven walks.

Royals Team Props

Royals vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Kansas City Royals and the Baltimore Orioles.

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