Orioles vs. Reds Prediction, Odds, Picks - April 18

Ryan O'Hearn and the Baltimore Orioles hit the field against Jake Fraley and the Cincinnati Reds at Oriole Park at Camden Yards on Friday, at 7:05 p.m. ET. The favored Orioles have -168 moneyline odds to win against the underdog Reds, who are listed at +141. Baltimore is favored on the run line (-1.5). The over/under is 9 runs for this game (with -121 odds to go over and +101 odds to go under).

Here's everything you need from a betting perspective on the Orioles-Reds game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Orioles Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and the Baltimore Orioles.

Orioles vs. Reds Game Information & Odds

• When: Friday, April 18, 2025 at 7:05 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN2 and FDSOH

Orioles vs. Reds Prediction

• Score Prediction: Reds 6, Orioles 5
• Total Prediction: Over 9 runs
• Win Probabilities: Orioles 51%, Reds 49%

Orioles vs. Reds Betting Insights

• This season, the Orioles have been favored nine times and won four of those games.
• Baltimore has not entered a game this season with shorter moneyline odds than -168.
• The moneyline for this contest implies a 62.7% chance of a victory for the Orioles.
• The Reds have been chosen as underdogs in 12 games this year and have walked away with the win five times (41.7%) in those games.
• Cincinnati has yet to play a game this season with longer moneyline odds than +141.
• Sportsbooks have implied with the moneyline set for this matchup that the Reds have a 41.5% chance of pulling out a win.

Orioles Recent Betting Performance

• The Orioles have a 3-3 record across the six games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all had set totals), the Orioles combined with their opponents to go over the total four times.
• The Orioles have put together a 4-6-0 record against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Cedric Mullins is the bat to watch in the Orioles lineup, leading the team in batting average (.291), home runs (4), and RBI (17).
• Including all MLB hitters, Mullins ranks 41st in batting average, fourth in on-base percentage, and 11th in slugging.
• O'Hearn is batting .326 with three doubles, three home runs and six walks.
• O'Hearn carries a four-game streak with at least one hit into this contest. During his last five outings he is hitting .429 with two home runs, two walks and four RBI.
• Adley Rutschman is batting .212 with two doubles, three home runs and eight walks.
• Tyler O'Neill is batting .265 with three doubles, a triple, two home runs and four walks.

Orioles Team Props

Reds Recent Betting Performance

• The Reds have played as underdogs in six of their past 10 games and have gone 3-3 in those contests.
• The Reds and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Reds have a record of 6-4-0 ATS over their last 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz paces the Reds with three long balls and runs batted in, driving in 18.
• Among all hitters in MLB, De La Cruz ranks 57th in home runs and sixth in RBI.
• TJ Friedl is hitting .268 with two doubles, a home run and five walks.
• Friedl ranks 149th in homers and 128th in RBI among all hitters in the majors.
• Matt McLain has three home runs, tops in the clubhouse.
• Jose Trevino is batting .286 with three doubles, a home run and three walks.

Reds Team Props

Guardians vs. Orioles Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Baltimore Orioles

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