Orioles vs. Mariners Prediction, Odds, Picks - June 5

The Baltimore Orioles and Ryan O'Hearn will hit the field against the Seattle Mariners and Julio Rodriguez on Thursday at 3:40 p.m. ET, in the final of a three-game series at T-Mobile Park. The Mariners are -109 moneyline underdogs in this matchup against the favorite Orioles (-110). Baltimore is a 1.5-run favorite (at +158 odds). An 8.5-run over/under is listed for the matchup.

Take a look at everything you need to know from a betting perspective on the Orioles-Mariners game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Mariners Game Information & Odds

• When: Thursday, June 5, 2025 at 3:40 p.m. ET
• Where: T-Mobile Park in Seattle, Washington
• How to watch on TV: ROOT Sports NW and MASN2

Orioles vs. Mariners Prediction

• Score Prediction: Mariners 4, Orioles 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Orioles 57%, Mariners 43%

Orioles vs. Mariners Betting Insights

• The Orioles have entered the game as favorites 33 times this season and won 13, or 39.4%, of those games.
• Baltimore has a record of 13-21, a 38.2% win rate, when favored by -110 or more by oddsmakers this season.
• The implied probability of a win from the Orioles, based on the moneyline, is 52.4%.
• The Mariners have been underdogs in 21 games this season and have come away with the win 12 times (57.1%) in those contests.
• Seattle has a win-loss record of 12-8 when favored by -109 or worse by bookmakers this year.
• The Mariners have an implied victory probability of 52.2% according to the moneyline set for this matchup.

Orioles Recent Betting Performance

• The Orioles have a 4-1 record over the five games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups, the Orioles and their opponents combined to hit the over on the run total two times (all 10 games had set totals).
• The Orioles have gone 5-5-0 against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• O'Hearn paces the Orioles with a .328 batting average.
• O'Hearn is 57th in home runs and 125th in RBI among all hitters in MLB.
• Jackson Holliday is hitting .264 with eight doubles, two triples, seven home runs and 11 walks.
• Holliday is 92nd in homers and 95th in RBI among all hitters in the majors.
• Gunnar Henderson has 11 doubles, two triples, seven home runs and 18 walks while hitting .257.
• Adley Rutschman is batting .214 with seven doubles, a triple, six home runs and 25 walks.
• Rutschman is riding a two-game hitting streak into this one. During his last five outings he is batting .238 with a home run, a walk and an RBI.

Orioles Team Props

Mariners Recent Betting Performance

• Over the past 10 games, the Mariners have been underdogs just once and lost that contest.
• The Mariners and their opponents have combined to hit the over five times in their last 10 games with a total.
• The Mariners have won three of their last 10 games against the spread.

Mariners Recent Stats

Mariners Player Insights

• Cal Raleigh paces the Mariners with 23 home runs and runs batted in, driving in 46.
• Raleigh's home run total puts him first in the majors, and he is seventh in RBI.
• Rodriguez is batting .248 with six doubles, two triples, 10 home runs and 20 walks.
• Rodriguez ranks 42nd among all hitters in the majors in homers, and 54th in RBI.
• J.P. Crawford has put up a team-high batting average of .279.
• Jorge Polanco is hitting .253 with six doubles, 10 home runs and nine walks.

Mariners Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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