Guardians vs. White Sox Prediction, Odds, Picks - August 9

The Cleveland Guardians and Chicago White Sox will meet on Saturday at Rate Field, at 7:10 p.m. ET, with Steven Kwan and Andrew Benintendi among those expected to step up at the plate. The favored Guardians have -133 moneyline odds against the underdog White Sox, who are listed at +112. Cleveland is favored on the run line (-1.5 with +129 odds). The over/under is 8.5 runs for the contest.

Check out everything you need to know from a betting perspective on the Guardians-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. White Sox Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and Chicago White Sox.

Guardians vs. White Sox Game Information & Odds

• When: Saturday, August 9, 2025 at 7:10 p.m. ET
• Where: Rate Field in Chicago, Illinois
• How to watch on TV: CHSN and CLEG

Guardians vs. White Sox Prediction

• Score Prediction: White Sox 5, Guardians 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Guardians 51%, White Sox 49%

Guardians vs. White Sox Betting Insights

• The Guardians have won 30, or 62.5%, of the 48 games they've played as favorites this season.
• This season Cleveland has won 17 of its 24 games, or 70.8%, when favored by at least -133 on the moneyline.
• The sportsbooks' moneyline implies a 57.1% chance of a victory for the Guardians.
• The White Sox have come away with 41 wins in the 114 contests they have been listed as the underdogs in this season.
• This season, Chicago has been victorious 40 times in 106 chances when named as an underdog of at least +112 or longer on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 47.2% chance of pulling out a win.

Guardians Recent Betting Performance

• The Guardians were the moneyline favorite for seven of their last 10 games, and they went 5-2 in those matchups.
• Over their last 10 outings -- all had a set run total -- the Guardians and their opponents combined to hit the over on the total six times.
• The Guardians' ATS record is 6-4-0 over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Jose Ramirez is the bat to watch in the Guardians lineup, leading the team in batting average (.296), home runs (23), and RBI (61).
• In all of the majors, Ramirez is 18th in home runs and 51st in RBI.
• Ramirez brings a hitting streak of two games into this matchup. In his last five games he is hitting .200 with a double, a home run, three walks and two RBIs.
• Kwan has 20 doubles, a triple, nine home runs and 40 walks while hitting .281.
• Kwan is 168th in homers and 161st in RBI on the year.
• Carlos Santana is hitting .230 with nine doubles, 11 home runs and 49 walks.
• Kyle Manzardo is hitting .239 with 14 doubles, two triples, 18 home runs and 34 walks.
• Manzardo has recorded at least one hit in two games in a row. During his last five outings he is hitting .214 with a double, two walks and an RBI.

Guardians Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and won four of those contests.
• In their last 10 games with a total, the White Sox and their opponents have failed to hit the over five times.
• The White Sox have a record of 5-5-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Benintendi has put up a team-high 14 home runs.
• Among all hitters in MLB, Benintendi's home run total ranks 93rd and his RBI tally is 123rd.
• Luis Robert has capitalized on opportunities as he paces his team with 46 runs batted in.
• Among all MLB hitters, Robert is 119th in home runs and 110th in RBI.
• Lenyn Sosa has accumulated a team-high batting average of .276.
• Mike Tauchman is batting .276 with 13 doubles, a triple, eight home runs and 31 walks.

White Sox Team Props

Guardians vs. White Sox Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and Chicago White Sox.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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