Giants vs. Dodgers Prediction, Odds, Picks - September 13

The San Francisco Giants and Los Angeles Dodgers will meet on Saturday at Oracle Park, at 9:05 p.m. ET, with Jung Hoo Lee and Shohei Ohtani among those expected to produce at the plate. The Dodgers are -102 moneyline underdogs for this matchup against the favorite Giants (-117). Los Angeles is a 1.5-run favorite (at +160 odds). The total is 7.5 runs for the contest (with -111 odds on the over and -109 odds on the under).

Take a look at everything you need from a betting perspective on the Giants-Dodgers game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Cardinals Highlights | MLB on FOX

Check out the best highlights between the St. Louis Cardinals and San Francisco Giants.

Giants vs. Dodgers Game Information & Odds

• When: Saturday, September 13, 2025 at 9:05 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: NBCS-BA and SportsNet LA

Giants vs. Dodgers Prediction

• Score Prediction: Giants 5, Dodgers 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Giants 52%, Dodgers 48%

Giants vs. Dodgers Betting Insights

• This season, the Giants have been favored 86 times and won 46, or 53.5%, of those games.
• This season San Francisco has won 43 of its 80 games, or 53.8%, when favored by at least -117 on the moneyline.
• The Giants have a 53.9% chance to win this game based on the implied probability of the moneyline.
• The Dodgers have won in seven, or 43.8%, of the 16 contests they have been named as odds-on underdogs this year.
• This season, Los Angeles has come away with a win four times in eight chances when named as an underdog of at least -102 or longer on the moneyline.
• The moneyline set for this matchup implies the Dodgers have a 50.5% chance of coming away with a victory in the contest.

Giants Recent Betting Performance

• The Giants went 5-2 over the seven games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 matchups -- all had a set run total -- the Giants and their opponents combined to go over the total five times.
• The Giants have an 8-2-0 record against the spread over their past 10 games.

Giants Recent Stats

Giants Player Insights

• Rafael Devers has a team-best 31 home runs and 102 runs batted in.
• Among all hitters in baseball, Devers ranks 11th in homers and seventh in RBI.
• Devers has collected a hit in two games in a row. During his last five outings he is hitting .176 with a double, four walks and three RBIs.
• Lee's .267 batting average paces his team.
• Lee is 231st in homers in baseball, and 141st in RBI.
• Willy Adames is hitting .229 with 20 doubles, two triples, 28 home runs and 70 walks.
• Matt Chapman is hitting .240 with 19 doubles, two triples, 21 home runs and 63 walks.

Giants Team Props

Dodgers Recent Betting Performance

• Bookmakers have not installed the Dodgers as underdogs in any of their last 10 games.
• The Dodgers and their opponents have combined to hit the over three times in their last 10 games with a total.
• The Dodgers have four wins against the spread in their last 10 chances.

Dodgers Recent Stats

Dodgers Player Insights

• Ohtani paces the Dodgers in home runs (48) and runs batted in (92).
• Among all batters in the majors, Ohtani's home run total ranks third and his RBI tally ranks 17th.
• Mookie Betts is batting .258 with 21 doubles, two triples, 18 home runs and 55 walks.
• Betts is 93rd in homers and 53rd in RBI among all hitters in the majors.
• Freddie Freeman paces the Dodgers with a team-high batting average of .291.
• Andy Pages has 23 doubles, a triple, 24 home runs and 27 walks while batting .271.

Dodgers Team Props

Giants vs. Cardinals Highlights | MLB on FOX

Check out the best highlights between the St. Louis Cardinals and San Francisco Giants.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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