Cubs vs. Giants Prediction, Odds, Picks - May 5

Landen Roupp will attempt to slow down Kyle Tucker and the Chicago Cubs when they play his San Francisco Giants on Monday at 7:40 p.m. ET. The Cubs have been listed as -177 moneyline favorites in this matchup with the Giants (+147). Chicago is the favorite on the run line (-1.5). The total is 7.5 runs for the contest.

Check out everything you need from a betting perspective on the Cubs-Giants game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Giants Game Information & Odds

• When: Monday, May 5, 2025 at 7:40 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and NBCS-BA

Cubs vs. Giants Prediction

• Score Prediction: Cubs 5, Giants 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Cubs 55%, Giants 45%

Cubs vs. Giants Betting Insights

• This season, the Cubs have won 13 out of the 19 games, or 68.4%, in which they've been favored.
• Chicago has not been bigger favorites this season than the -177 moneyline set for this game.
• The Cubs have a 63.9% chance to win this game based on the implied probability of the moneyline.
• The Giants have won in seven, or 53.8%, of the 13 contests they have been named as odds-on underdogs this year.
• San Francisco has played as an underdog of +147 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies the Giants have a 40.5% chance of coming away with a victory in the contest.

Cubs Recent Betting Performance

• The Cubs were the moneyline favorite for eight of their last 10 games, and went 5-3 in those matchups.
• In their last 10 outings (all 10 of them had set totals), the Cubs and their opponents combined to hit the over five times.
• The Cubs are 5-5-0 against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Not only does Tucker lead the Cubs in hitting with his .292 average, he also is their foremost power hitter with nine home runs and 30 RBI.
• Among all hitters in the majors, Tucker is sixth in homers and fifth in RBI.
• Tucker carries a four-game hitting streak into this matchup. During his last five outings he is batting .316 with two home runs, three walks and four RBI.
• Pete Crow-Armstrong has shown off his power as he leads his team with nine home runs.
• Crow-Armstrong ranks sixth in home runs and 11th in RBI among all hitters in the majors.
• Crow-Armstrong has three straight games with at least one hit. During his last five outings he is hitting .200 with three home runs and five RBI.
• Carson Kelly is batting .368 with two doubles, a triple, seven home runs and 17 walks.
• Kelly has at least one base hit in five games in a row. In his last five games he is hitting .421 with a double, a home run, three walks and four RBI.
• Ian Happ is batting .286 with nine doubles, two home runs and 21 walks.
• Happ takes a six-game streak with at least one hit into this one. During his last 10 outings he is batting .325 with four doubles, six walks and three RBI.

Cubs Team Props

Giants Recent Betting Performance

• The Giants have been underdogs once in the past 10 games and lost that contest.
• In their last 10 games with a total, the Giants and their opponents are 5-5-0 when it comes to hitting the over.
• The Giants have a record of 3-7-0 ATS over their last 10 games.

Giants Recent Stats

Giants Player Insights

• Jung Hoo Lee leads the Giants with a .305 batting average.
• Lee ranks 129th in homers and 36th in RBI among all hitters in MLB.
• Michael Yastrzemski is batting .283 with seven doubles, five home runs and 17 walks.
• Among all major league hitters, Yastrzemski is 57th in homers and 62nd in RBI.
• Matt Chapman has seven home runs, best in the lineup.
• Wilmer Flores paces the Giants with seven long balls and runs batted in, driving in 31.

Giants Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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