Cardinals vs. Brewers Prediction, Odds, Picks - April 25

Matthew Liberatore and Chad Patrick are the projected starters when the St. Louis Cardinals and Milwaukee Brewers face off on Friday at Busch Stadium. The Cardinals are the favorite in this one, at -132, while the underdog Brewers have +112 odds to win. St. Louis is a 1.5-run favorite (at +159 odds). An 8-run over/under is set for this matchup.

Take a look at everything you need from a betting perspective on the Cardinals-Brewers game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Brewers Game Information & Odds

• When: Friday, April 25, 2025 at 8:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and FDSWI

Cardinals vs. Brewers Prediction

• Score Prediction: Brewers 6, Cardinals 5
• Total Prediction: Over 8 runs
• Win Probabilities: Cardinals 50%, Brewers 50%

Cardinals vs. Brewers Betting Insights

• The Cardinals have entered the game as favorites six times this season and won twice.
• St. Louis has a record of 1-2 in games when oddsmakers favor them by at least -132 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Cardinals have a 56.9% chance to win.
• The Brewers have come away with three wins in the 12 contests they have been listed as the underdogs in this season.
• This season, Milwaukee has been victorious two times in 10 chances when named as an underdog of at least +112 or worse on the moneyline.
• The moneyline set for this matchup implies the Brewers have a 47.2% chance of coming away with a victory in the contest.

Cardinals Recent Betting Performance

• In the last 10 games, the Cardinals were listed as the moneyline favorite by oddsmakers just once, a game they won.
• In their last 10 outings, the Cardinals and their opponents combined to hit the over on the run total five times (all 10 games had set totals).
• The Cardinals' ATS record is 5-5-0 over their past 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Brendan Donovan leads the Cardinals with a team-high batting average of .356.
• Of all hitters in the majors, Donovan ranks 88th in homers and 54th in RBI.
• Donovan takes a hitting streak of two games into this game. In his last five games he is batting .263 with a double, a home run, a walk and two RBI.
• Lars Nootbaar has shown off his power as he leads his team with four home runs and 14 RBI.
• Nootbaar is 49th in home runs and 44th in RBI among all hitters in the majors.
• Nolan James Arenado has eight doubles, two home runs and 13 walks while hitting .267.
• Victor Scott II has five doubles, a triple, a home run and eight walks while hitting .275.

Cardinals Team Props

Brewers Recent Betting Performance

• The Brewers have played as underdogs in six of their past 10 games and won two of those contests.
• In their last 10 games with a total, the Brewers and their opponents have combined to hit the over four times.
• The Brewers have six wins against the spread in their last 10 chances.

Brewers Recent Stats

Brewers Player Insights

• Brice Turang leads the Brewers with a .346 batting average.
• Among all hitters in the majors, Turang is 88th in home runs and 44th in RBI.
• Turang takes a hitting streak of three games into this matchup. In his last five games he is batting .500 with a double, three walks and four RBI.
• Jackson Chourio has been a reliable source of runs this year, leading the lineup with five home runs and 20 RBI.
• Chourio ranks 32nd in homers and 11th in RBI among all batters in the majors.
• Christian Yelich paces the Brewers in home runs (five) and runs batted in (20).
• Sal Frelick is batting .312 with three doubles, two triples, a home run and 11 walks.

Brewers Team Props

Brewers vs. Giants Highlights | MLB on FOX

Check out the best highlights between the Milwaukee Brewers and the San Francisco Giants.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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St. Louis Cardinals

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