Brewers vs. Cubs NLDS Game 2 Prediction, Odds, Picks - October 6

The Milwaukee Brewers will host the Chicago Cubs in the second game of the NLDS on Monday at 9:08 p.m. ET, live on TBS, truTV, and HBO Max from American Family Field. The Cubs will look to bounce back after falling behind in the series in Game 1. Bookmakers list the Brewers as -136 favorites on the moneyline, while giving the underdog Cubs +115 moneyline odds to win. Milwaukee is the favorite on the run line (-1.5 with +149 odds). The contest's over/under is set at 7.5 runs.

Here is everything you need to know from a betting perspective on the Brewers-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Brewers vs. Cubs Game Information & Odds

• When: Monday, October 6, 2025 at 9:08 p.m. ET
• Where: American Family Field in Milwaukee, Wisconsin
• How to watch on TV: TBS, truTV, and HBO Max

Brewers vs. Cubs Prediction

• Score Prediction: Brewers 4, Cubs 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Brewers 55%, Cubs 45%

Brewers vs. Cubs Betting Insights

• The Brewers have been favorites in 98 games this season and won 61 (62.2%) of those contests.
• Milwaukee has a record of 43-15 in games when sportsbooks favor them by at least -136 on the moneyline.
• The sportsbooks' moneyline implies a 57.6% chance of a victory for the Brewers.
• The Cubs have won in 18, or 38.3%, of the 47 contests they have been named as odds-on underdogs this year.
• Chicago has a win-loss record of 5-11 when favored by +115 or worse by oddsmakers this year.
• The Cubs have an implied victory probability of 46.5% according to the moneyline set by sportsbooks for this matchup.

Brewers Recent Betting Performance

• The Brewers have a 3-6 record from the nine games they were moneyline favorites over their last 10 matchups.
• Over their last 10 matchups -- all had a set run total -- the Brewers and their opponents combined to go over the total four times.
• The Brewers have put together a 3-7-0 record against the spread over their past 10 games.

Brewers Recent Stats

Brewers Player Insights

• Brice Turang's .288 average leads the Brewers this year. His resume also includes 18 homers and driven in 81 RBI.
• In all of the majors, Turang ranks 105th in home runs and 52nd in RBI.
• Turang has collected a hit in five straight games. During his last five outings he is batting .421 with three doubles, three walks and five RBIs.
• Christian Yelich has put his power on display as he leads his team with 29 home runs and 103 RBI.
• Yelich ranks 34th in homers and 11th in RBI among all major league hitters this season.
• William Contreras is hitting .260 with 28 doubles, 17 home runs and 84 walks.
• Jackson Chourio is batting .270 with 35 doubles, four triples, 21 home runs and 30 walks.
• Chourio brings a three-game streak with at least one hit into this one. During his last five outings he is hitting .368 with two doubles, a home run, two walks and four RBIs.

Brewers Team Props

Cubs Recent Betting Performance

• The Cubs have been underdogs twice in the last 10 games and lost both contests.
• The Cubs and their opponents have combined to hit the over six times in their last 10 games with a total.
• The Cubs have a record of 6-4-0 ATS over their last 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker has 25 doubles, four triples, 22 home runs and 87 walks while batting .266.
• Tucker ranks 65th in homers and 77th in RBI among all hitters in the big leagues.
• Nico Hoerner has a club-high .297 batting average.
• Hoerner is currently 264th in home runs and 123rd in RBI in the big leagues.
• Pete Crow-Armstrong has 37 doubles, four triples, 31 home runs and 29 walks while batting .247.
• Seiya Suzuki has racked up a team-leading 103 runs batted in.

Cubs Team Props

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