Notre Dame vs. Duke Prediction, Odds, Picks - September 30

Updated Sep. 29, 2023 9:15 a.m. ET

FOX Sports

The No. 11 Notre Dame Fighting Irish (4-1), who have college football's sixth-ranked pass defense, take on the No. 17 Duke Blue Devils (4-0) and their third-ranked passing defense on Saturday, September 30, 2023. The Fighting Irish are 5.5-point favorites. The game's point total is 52.5.

Facing the Ohio State Buckeyes in their most recent contest, the Fighting Irish lost 17-14. Last time out, the Blue Devils defeated the UConn Huskies, with 41-7 being the final score.

Notre Dame vs. Duke Game Information & Odds

When: Saturday, September 30, 2023 at 7:30 PM ET
Location: Brooks Field at Wallace Wade Stadium in Wilmington, North Carolina
TV: ABC
Live boxscore on FOX Sports

Notre Dame vs Duke Betting Information updated as of September 29, 2023, 8:46 AM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Notre Dame	-5.5 (-110)	-219	+179	52.5	-110	-110

Notre Dame vs. Duke Prediction

Pick ATS: Duke (+5.5)
Pick OU: Under (52.5)
Prediction: Duke 25, Notre Dame 23

Learn more about the Notre Dame Fighting Irish vs. the Duke Blue Devils game on FOX Sports!

Notre Dame vs. Duke Betting Insights

Based on the spread and over/under, the implied score for the game is Fighting Irish 29, Blue Devils 24.
The Fighting Irish have a 68.7% chance to win this contest based on the moneyline's implied probability. The Blue Devils hold a 35.8% implied probability.
Notre Dame is 3-1-1 ATS this season.
Duke has covered three times in three matchups with a spread this season.

Notre Dame vs. Duke: 2023 Stats Comparison

	Notre Dame	Duke
Off. Points per Game (Rank)	39.6 (4)	37.3 (29)
Def. Points per Game (Rank)	12.8 (21)	8.8 (4)
Turnovers Allowed (Rank)	2 (3)	3 (13)
Turnovers Forced (Rank)	5 (74)	8 (18)

Notre Dame 2023 Key Players

Name	Position	Stats
Sam Hartman	QB	1,236 YDS (70.4%) / 14 TD / 0 INT -9 RUSH YDS / 2 RUSH TD / -1.8 RUSH YPG
Audric Estime	RB	591 YDS / 5 TD / 118.2 YPG / 7.7 YPC 5 REC / 55 REC YDS / 0 REC TD / 11.0 REC YPG
Holden Staes	TE	6 REC / 123 YDS / 4 TD / 24.6 YPG
Chris Tyree	WR	9 REC / 241 YDS / 2 TD / 48.2 YPG
Jack Kiser	LB	26 TKL / 0.0 TFL / 1.0 SACK
Thomas Harper	S	18 TKL / 0.0 TFL / 1.0 SACK
Jordan Botelho	DL	13 TKL / 2.0 TFL / 2.0 SACK
Xavier Watts	S	18 TKL / 0.0 TFL / 1 INT / 2 PD

Duke 2023 Key Players

Name	Position	Stats
Riley Leonard	QB	778 YDS (67.7%) / 2 TD / 0 INT 238 RUSH YDS / 4 RUSH TD / 59.5 RUSH YPG
Jordan Waters	RB	258 YDS / 7 TD / 64.5 YPG / 6.6 YPC 5 REC / 76 REC YDS / 0 REC TD / 19.0 REC YPG
Jordan Moore	WR	20 REC / 246 YDS / 2 TD / 61.5 YPG
Jaquez Moore	RB	184 YDS / 2 TD / 46.0 YPG / 5.3 YPC 2 REC / 46 REC YDS / 0 REC TD / 11.5 REC YPG
Brandon Johnson	DB	19 TKL / 5.0 TFL / 1.0 SACK
Chandler Rivers	CB	23 TKL / 0.0 TFL
Dorian Mausi	LB	18 TKL / 1.0 TFL / 1 INT / 1 PD
Jaylen Stinson	S	21 TKL / 0.0 TFL