Missouri vs. South Carolina Prediction, Odds, Picks - October 21

The No. 20 Missouri Tigers (6-1), who have college football's 18th-ranked passing offense, take on the South Carolina Gamecocks (2-4) and their 13th-ranked passing attack on Saturday, October 21, 2023. The Tigers are 7.5-point favorites. The over/under is set at 57.5 for the contest.

The Tigers' last game was against the Kentucky Wildcats, and they won by a score of 38-21. In their most recent game, the Gamecocks lost versus the Florida Gators, 41-39.

Missouri vs. South Carolina Game Information & Odds

• When: Saturday, October 21, 2023 at 3:30 PM ET
• Location: Faurot Field at Memorial Stadium in Columbia, Missouri
• TV: SEC Network
• Live boxscore on FOX Sports

Missouri vs. South Carolina Prediction

• Pick ATS: Missouri (-7.5)
  
• Pick OU: Over (57.5)
  
• Prediction: Missouri 37, South Carolina 22

Learn more about the Missouri Tigers vs. the South Carolina Gamecocks game on FOX Sports!

Missouri vs. South Carolina Betting Insights

• Based on the spread and over/under, the implied score for the game is Tigers 32, Gamecocks 25.
• The Tigers have a 75.7% chance to collect the win in this game based on the moneyline's implied probability. The Gamecocks hold a 29.0% implied probability.
• Missouri has won four games against the spread this season, while failing to cover twice.
• South Carolina has covered three times in six matchups with a spread this season.

Missouri vs. South Carolina: Head-to-Head

• Over their last two meetings, Missouri has tallied two wins against South Carolina.
• The last two times the Tigers have gone up against the Gamecocks, they have posted a 2-0 record against the spread. The scoring has gone over the total on one occasion.
• South Carolina has been outscored by 16 points in its last two tilts versus Missouri.

Missouri vs. South Carolina: 2023 Stats Comparison

Missouri 2023 Key Players

South Carolina 2023 Key Players