Michigan vs. Washington Prediction, Odds, Picks - October 18, 2025

Updated Oct. 18, 2025 9:04 a.m. ET

FOX Sports

The Washington Huskies (5-1) and the seventh-ranked run defense will visit the Michigan Wolverines (4-2) and the 19th-ranked run offense on Saturday, October 18, 2025. The Huskies are 4.5-point underdogs. The total for this matchup has been set at 50.5 points.

The Wolverines lost versus the USC Trojans in their last game, 31-13. In their last game, the Huskies won against the Rutgers Scarlet Knights, 38-19.

Keep up with college football all season on FOX Sports.

Michigan vs. Washington Game Information & Odds

When: Saturday, October 18, 2025 at 12 p.m. ET
Location: Michigan Stadium in Ann Arbor, Michigan
TV: FOX
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Michigan vs Washington Betting Information updated as of October 18, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Michigan	-4.5 (-112)	-200	+166	50.5	-111	-109

Michigan vs. Washington Prediction

Pick ATS: Washington (+4.5)
Pick OU: Over (50.5)
Prediction: Washington 28, Michigan 24

Predictions are made by the Data Skrive betting model.

Learn more about the Michigan Wolverines vs. the Washington Huskies game on FOX Sports!

Michigan vs. Washington Betting Insights

Per the spread and over/under, the implied score for the matchup is Wolverines 28, Huskies 23.
The Wolverines have a 66.7% chance to collect the win in this meeting based on the moneyline's implied probability. The Huskies hold a 37.6% implied probability.
Michigan has a record of 2-4-0 against the spread this season.
Washington has covered twice in five games with a spread this year.

Michigan vs. Washington: Head-to-Head

Michigan has a 2-1 record against Washington in their last three matchups.
The Wolverines have a 2-1 record ATS in those games, while the two teams have gone over the point total on one occasion.
Washington has been outscored by 32 points in its last three tilts against Michigan.

Michigan vs. Washington: 2025 Stats Comparison

	Michigan	Washington
Off. Points per Game (Rank)	29.5 (65)	39.2 (19)
Def. Points per Game (Rank)	18.7 (28)	19.7 (33)
Turnovers Allowed (Rank)	5 (19)	3 (6)
Turnovers Forced (Rank)	11 (19)	8 (55)

Michigan 2025 Key Players

Name	Position	Stats
Justice Haynes	RB	705 YDS / 8 TD / 117.5 YPG / 7.4 YPC
Bryce Underwood	QB	1,210 YDS (59.7%) / 5 TD / 2 INT 177 RUSH YDS / 3 RUSH TD / 29.5 RUSH YPG
Jordan Marshall	RB	301 YDS / 3 TD / 50.2 YPG / 5.1 YPC
Donaven McCulley	WR	22 REC / 348 YDS / 2 TD / 58 YPG
Cole Sullivan	LB	18 TKL / 4 TFL / 2 SACK / 2 INT
Jaishawn Barham	LB	17 TKL / 4 TFL / 3 SACK
Jimmy Rolder	LB	24 TKL / 1 TFL / 1 SACK
Derrick Moore	DL	9 TKL / 2 TFL / 2.5 SACK

Washington 2025 Key Players

Name	Position	Stats
Demond Williams Jr.	QB	1,628 YDS (74.1%) / 10 TD / 1 INT 382 RUSH YDS / 4 RUSH TD / 63.7 RUSH YPG
Jonah Coleman	RB	518 YDS / 11 TD / 86.3 YPG / 5.4 YPC 20 REC / 243 REC YDS / 1 REC TD / 40.5 REC YPG
Denzel Boston	WR	30 REC / 444 YDS / 6 TD / 74 YPG
Dezmen Roebuck	WR	18 REC / 331 YDS / 2 TD / 66.2 YPG
Alex McLaughlin	DB	43 TKL / 1 TFL / 2 INT / 2 PD
Jacob Lane	DL	24 TKL / 4 TFL / 2.5 SACK
Makell Esteen	DB	27 TKL / 0 TFL / 0.5 SACK / 2 INT
Deven Bryant	LB	36 TKL / 0 TFL