Kentucky vs. Eastern Michigan Prediction, Odds, Picks - September 13, 2025

Updated Sep. 13, 2025 3:04 p.m. ET

Data Skrive

The Kentucky Wildcats (1-1) are massive 26.5-point favorites on Saturday, September 13, 2025 against the Eastern Michigan Eagles (0-2). The contest's over/under is set at 49.5.

The Wildcats lost to the Ole Miss Rebels, 30-23, in their last game. Last time out, the Eagles fell to the LIU Sharks, with 28-23 being the final score.

Keep up with college football all season on FOX Sports.

Kentucky vs. Eastern Michigan Game Information & Odds

When: Saturday, September 13, 2025 at 7:30 p.m. ET
Location: Kroger Field in Lexington, Kentucky
TV: ESPNU
Live Box Score on FOX Sports

Kentucky vs Eastern Michigan Betting Information updated as of September 13, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Kentucky	-26.5 (-110)	-4167	+1540	49.5	-110	-113

Kentucky vs. Eastern Michigan Prediction

Pick ATS: Eastern Michigan (+26.5)
Pick OU: Over (49.5)
Prediction: Kentucky 38, Eastern Michigan 24

Predictions are made by the Data Skrive betting model.

Learn more about the Kentucky Wildcats vs. the Eastern Michigan Eagles game on FOX Sports!

Kentucky vs. Eastern Michigan Betting Insights

Based on the spread and over/under, the implied score for the game is Wildcats 38, Eagles 12.
The Wildcats have a 97.7% chance to win this game based on the moneyline's implied probability. The Eagles have a 6.1% implied probability.
Kentucky has won one game against the spread this season.
Eastern Michigan has compiled a 0-2-0 record against the spread this season.

Kentucky vs. Eastern Michigan: 2025 Stats Comparison

	Kentucky	Eastern Michigan
Off. Points per Game (Rank)	23.5 (94)	25 (87)
Def. Points per Game (Rank)	23 (78)	40 (124)
Turnovers Allowed (Rank)	2 (54)	0 (1)
Turnovers Forced (Rank)	3 (37)	0 (126)

Kentucky 2025 Key Players

Name	Position	Stats
Seth McGowan	RB	171 YDS / 3 TD / 85.5 YPG / 5.2 YPC
Dante Dowdell	RB	185 YDS / 1 TD / 92.5 YPG / 6.6 YPC
Zach Calzada	QB	234 YDS (47.2%) / 0 TD / 1 INT 23 RUSH YDS / 1 RUSH TD / 11.5 RUSH YPG
Jay Maclin	WR	3 REC / 67 YDS / 0 TD / 33.5 YPG
Alex Afari	LB	23 TKL / 3 TFL / 1 SACK
Steven Soles Jr.	LB	6 TKL / 0 TFL / 2 SACK
Ty Bryant	DB	16 TKL / 0 TFL / 2 INT / 2 PD
Jonquis Hardaway	DB	9 TKL / 0 TFL / 1 INT / 1 PD

Eastern Michigan 2025 Key Players

Name	Position	Stats
Dontae McMillan	RB	136 YDS / 1 TD / 68 YPG / 8 YPC 4 REC / 68 REC YDS / 1 REC TD / 34 REC YPG
Noah Kim	QB	437 YDS (65.1%) / 3 TD / 0 INT 24 RUSH YDS / 0 RUSH TD / 12 RUSH YPG
Terry Lockett Jr.	WR	13 REC / 140 YDS / 0 TD / 70 YPG
Joshua Long	TE	5 REC / 63 YDS / 1 TD / 31.5 YPG
Messiah Blair	DL	6 TKL / 0 TFL / 1 SACK
Bryce Llewellyn	DB	12 TKL / 1 TFL
Carter Evans	DL	8 TKL / 1 TFL
Juan Salas Jr.	DB	8 TKL / 0 TFL