
College Football Top 25 Week 3 2025 Predictions, Betting Odds & TV Schedule
Updated Sep. 13, 2025 2:25 p.m. ET
Data Skrive
The No. 6 Georgia Bulldogs and the No. 15 Tennessee Volunteers take the field in one of 21 games on the college football slate in Week 3 that include a ranked team.
With Week 3 in college football upon us, stay on top of the most current betting odds with our preview below.
Check out the full college football schedule on FOX Sports! Or visit FOX Sports' college football hub for everything you need to make the most of this season’s action.
Week 3 Betting Lines & Game Info
No. 22 Indiana Hoosiers vs. Indiana State Sycamores
Odds & Prediction
- Spread: Hoosiers (-47.5)
- Moneyline: Hoosiers , Sycamores
- Total: 60.5 points
- Prediction:
How to Watch
- Game Date: Friday, Sept. 12
- Game Time: 6:30 p.m. ET
- TV Channel: BTN
- Location: Bloomington, Indiana
- Box Score
Temple Owls vs. No. 13 Oklahoma Sooners
Odds & Prediction
- Spread: Sooners (-23.5)
- Moneyline: Sooners -2381, Owls +1200
- Total: 51.5 points
- Prediction: Oklahoma 25, Temple 20
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12 p.m. ET
- TV Channel: ESPN2
- Location: Philadelphia, Pennsylvania
- Box Score
Georgia Tech Yellow Jackets vs. No. 12 Clemson Tigers
Odds & Prediction
- Spread: Tigers (-3)
- Moneyline: Tigers -142, Yellow Jackets +120
- Total: 51.5 points
- Prediction: Georgia Tech 23, Clemson 18
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12 p.m. ET
- TV Channel: ESPN
- Location: Atlanta, Georgia
- Box Score
Northwestern Wildcats vs. No. 4 Oregon Ducks
Odds & Prediction
- Spread: Ducks (-25.5)
- Moneyline: Ducks -3571, Wildcats +1500
- Total: 50.5 points
- Prediction: Oregon 28, Northwestern 21
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12 p.m. ET
- TV Channel: FOX
- Location: Evanston, Illinois
- Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
No. 19 Alabama Crimson Tide vs. Wisconsin Badgers
Odds & Prediction
- Spread: Crimson Tide (-19.5)
- Moneyline: Crimson Tide -1099, Badgers +700
- Total: 45.5 points
- Prediction: Alabama 28, Wisconsin 19
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12 p.m. ET
- TV Channel: ABC
- Location: Tuscaloosa, Alabama
- Box Score
No. 23 Michigan Wolverines vs. Central Michigan Chippewas
Odds & Prediction
- Spread: Wolverines (-28.5)
- Moneyline: Wolverines -4545, Chippewas +1700
- Total: 43.5 points
- Prediction: Michigan 32, Central Michigan 13
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12 p.m. ET
- TV Channel: BTN
- Location: Ann Arbor, Michigan
- Box Score
No. 24 Auburn Tigers vs. South Alabama Jaguars
Odds & Prediction
- Spread: Tigers (-25.5)
- Moneyline: Tigers -3571, Jaguars +1500
- Total: 56.5 points
- Prediction: Auburn 33, South Alabama 26
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 12:45 p.m. ET
- TV Channel: SEC Network
- Location: Auburn, Alabama
- Box Score
No. 25 Missouri Tigers vs. Louisiana Ragin' Cajuns
Odds & Prediction
- Spread: Tigers (-26.5)
- Moneyline: Tigers -4545, Ragin' Cajuns +1700
- Total: 47.5 points
- Prediction: Missouri 35, Louisiana 14
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 1 p.m. ET
- TV Channel: SEC Network+
- Location: Columbia, Missouri
- Box Score
No. 15 Tennessee Volunteers vs. No. 6 Georgia Bulldogs
Odds & Prediction
- Spread: Bulldogs (-3.5)
- Moneyline: Bulldogs -175, Volunteers +145
- Total: 50.5 points
- Prediction: Tennessee 35, Georgia 27
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 3:30 p.m. ET
- TV Channel: ABC
- Location: Knoxville, Tennessee
- Box Score
No. 21 Texas Tech Red Raiders vs. Oregon State Beavers
Odds & Prediction
- Spread: Red Raiders (-23.5)
- Moneyline: Red Raiders -2381, Beavers +1200
- Total: 62.5 points
- Prediction: Texas Tech 37, Oregon State 29
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 3:30 p.m. ET
- TV Channel: FOX
- Location: Lubbock, Texas
- Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
No. 2 Penn State Nittany Lions vs. Villanova Wildcats
Odds & Prediction
- Spread: Nittany Lions (-47.5)
- Moneyline: Nittany Lions , Wildcats
- Total: 56.5 points
- Prediction:
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 3:30 p.m. ET
- TV Channel: FS1
- Location: University Park, Pennsylvania
- Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
Arkansas State Red Wolves vs. No. 14 Iowa State Cyclones
Odds & Prediction
- Spread: Cyclones (-21.5)
- Moneyline: Cyclones -1639, Red Wolves +950
- Total: 56.5 points
- Prediction: Iowa State 33, Arkansas State 20
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 4 p.m. ET
- TV Channel: ESPN2
- Location: Jonesboro, Arkansas
- Box Score
No. 7 Texas Longhorns vs. UTEP Miners
Odds & Prediction
- Spread: Longhorns (-38.5)
- Moneyline: Longhorns , Miners
- Total: 51.5 points
- Prediction: Texas 29, UTEP 9
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 4:15 p.m. ET
- TV Channel: SEC Network
- Location: Austin, Texas
- Box Score
No. 5 Miami (FL) Hurricanes vs. No. 18 South Florida Bulls
Odds & Prediction
- Spread: Hurricanes (-17.5)
- Moneyline: Hurricanes -800, Bulls +550
- Total: 56.5 points
- Prediction: Miami (FL) 25, South Florida 19
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 4:30 p.m. ET
- TV Channel: The CW
- Location: Miami Gardens, Florida
- Box Score
No. 17 Ole Miss Rebels vs. Arkansas Razorbacks
Odds & Prediction
- Spread: Rebels (-5.5)
- Moneyline: Rebels -198, Razorbacks +164
- Total: 60.5 points
- Prediction: Ole Miss 39, Arkansas 26
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7 p.m. ET
- TV Channel: ESPN
- Location: Oxford, Mississippi
- Box Score
No. 1 Ohio State Buckeyes vs. Ohio Bobcats
Odds & Prediction
- Spread: Buckeyes (-28.5)
- Moneyline: Buckeyes -5000, Bobcats +1800
- Total: 49.5 points
- Prediction: Ohio State 23, Ohio 11
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7 p.m. ET
- TV Channel: Peacock
- Location: Columbus, Ohio
- Box Score
No. 9 Illinois Fighting Illini vs. Western Michigan Broncos
Odds & Prediction
- Spread: Fighting Illini (-27.5)
- Moneyline: Fighting Illini -6667, Broncos +2000
- Total: 50.5 points
- Prediction: Illinois 36, Western Michigan 19
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7 p.m. ET
- TV Channel: FS1
- Location: Champaign, Illinois
- Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
No. 3 LSU Tigers vs. Florida Gators
Odds & Prediction
- Spread: Tigers (-6.5)
- Moneyline: Tigers -250, Gators +205
- Total: 47.5 points
- Prediction: LSU 18, Florida 13
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7:30 p.m. ET
- TV Channel: ABC
- Location: Baton Rouge, Louisiana
- Box Score
No. 8 Notre Dame Fighting Irish vs. No. 16 Texas A&M Aggies
Odds & Prediction
- Spread: Fighting Irish (-6.5)
- Moneyline: Fighting Irish -245, Aggies +200
- Total: 50.5 points
- Prediction: Notre Dame 30, Texas A&M 29
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7:30 p.m. ET
- TV Channel: NBC
- Location: South Bend, Indiana
- Box Score
No. 11 South Carolina Gamecocks vs. Vanderbilt Commodores
Odds & Prediction
- Spread: Gamecocks (-3)
- Moneyline: Gamecocks -148, Commodores +124
- Total: 48.5 points
- Prediction: South Carolina 26, Vanderbilt 24
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 7:45 p.m. ET
- TV Channel: SEC Network
- Location: Columbia, South Carolina
- Box Score
Wyoming Cowboys vs. No. 20 Utah Utes
Odds & Prediction
- Spread: Utes (-23.5)
- Moneyline: Utes -2778, Cowboys +1300
- Total: 47.5 points
- Prediction: Utah 19, Wyoming 13
How to Watch
- Game Date: Saturday, Sept. 13
- Game Time: 8 p.m. ET
- TV Channel: CBS Sports Network
- Location: Laramie, Wyoming
- Box Score
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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