Arizona vs. Colorado Prediction, Odds, Picks - November 1, 2025

The Colorado Buffaloes (3-5) are 4-point underdogs in a home conference matchup against the Arizona Wildcats (4-3) on Saturday, November 1, 2025 at Folsom Field. The total for this matchup has been set at 52.5 points.

The Wildcats lost against the Houston Cougars in their most recent game, 31-28. The Buffaloes lost against the Utah Utes in their last game, 53-7.

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Arizona vs. Colorado Game Information & Odds

• When: Saturday, November 1, 2025 at 7 p.m. ET
• Location: Folsom Field in Boulder, Colorado
• TV: FS1
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

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Arizona vs. Colorado Prediction

• Pick ATS: Colorado (+4)
  
• Pick OU: Under (52.5)
  
• Prediction: Arizona 26, Colorado 25

Predictions are made by the Data Skrive betting model.

Learn more about the Arizona Wildcats vs. the Colorado Buffaloes game on FOX Sports!

Arizona vs. Colorado Betting Insights

• Based on the spread and over/under, the implied score for the game is Wildcats 28, Buffaloes 24.
• The Wildcats have a 64.9% chance to collect the win in this game based on the moneyline's implied probability. The Buffaloes have a 39.5% implied probability.
• Arizona has put together a 3-3-0 ATS record so far this year.
• Colorado has put together a 4-4-0 ATS record so far this year.

Arizona vs. Colorado: Head-to-Head

• Arizona and Colorado have been matched up evenly over their last four meetings, sharing the same 2-2 record.
• The Buffaloes carry a 3-1 record ATS in those games, while the two teams have gone over the total on two occasions.
• Arizona has been outpaced by 35 points in its last four tilts versus Colorado.

Arizona vs. Colorado: 2025 Stats Comparison

Arizona 2025 Key Players

Colorado 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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