Duke vs. Michigan State Prediction, How to Watch, Odds, Channel - Dec 6

Updated Dec. 5, 2025 8:27 p.m. ET

Data Skrive

The No. 4 Duke Blue Devils (9-0) take a nine-game win streak into a road matchup with the No. 7 Michigan State Spartans (8-0), winners of eight straight. The contest tips at 12 p.m. ET (on FOX) on Saturday, December 6, 2025.

The Blue Devils are a slight 1.5-point favorite against the Spartans. The game features an over/under of 139.5.

Continue reading to get all the information before wagering on the Duke-Michigan State matchup.

Duke vs. Michigan State How to Watch & Odds

When: Saturday, December 6, 2025 at 12 p.m. ET
Where: Jack Breslin Students Events Center in East Lansing, Michigan
TV: FOX
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Blue Devils vs Spartans Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Blue Devils	-1.5	-108	-112	139.5	-112	-108	-116	-103

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Duke vs. Michigan State Prediction

Pick ATS: Michigan State (+1.5)
Pick OU: Over (139.5)
Prediction: Michigan State 73, Duke 71

Learn more about the Duke Blue Devils vs. the Michigan State Spartans game on FOX Sports!

Duke vs. Michigan State Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the game is Blue Devils 70, Spartans 69.
The Blue Devils have a 53.7% chance to win this game based on the moneyline's implied probability.
The Spartans have a 50.7% implied probability to come out on top.

Key Spread Facts

Duke has won five games against the spread this season, while failing to cover four times.
Michigan State has put together a 5-3-0 ATS record so far this year.
Duke has covered the spread five times this season (5-4 ATS) when playing as at least 1.5-point favorites.
Michigan State has been an underdog by 1.5 points or more once this season, and covered the spread.

Key Total Facts

Blue Devils games have finished with more than 139.5 points seven times so far this year.
So far this year, four Spartans games have featured over 139.5 points scored.
The Blue Devils and Spartans average 167.7 points per game combined, which is 28.2 more than the over/under for this matchup.

Key Moneyline Facts

Duke has won all six games when favored on the moneyline this season.
Michigan State won the only game it has played as the underdog this season.
Duke has won all six games it played as a moneyline favorite with odds of -116 or shorter.
Michigan State has played as an underdog of -103 or more once this season and won that game.

Duke vs. Michigan State: 2025-26 Stats Comparison

	Duke	Michigan State
Points Scored Per Game (Rank)	89.1 (32)	78.6 (166)
Points Allowed (Rank)	59.6 (4)	60.4 (6)
Rebounds (Rank)	10.8 (99)	12.8 (21)
3pt Made (Rank)	10.1 (48)	6.6 (285)
Assists (Rank)	19.1 (23)	19.3 (16)
Turnovers (Rank)	10.4 (80)	11.4 (149)

Duke 2025-26 Key Players

Blue Devils Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Cameron Boozer	9	23.6	9.3	3.6	1.8	1	1.7
Patrick Ngongba II	9	12.6	6.4	2.4	0.4	1.6	0.4
Isaiah Evans	9	12.6	3.3	1.8	0.4	1.3	2.2
Caleb Foster	9	8.9	3.4	3	0.6	0	1.4
Dame Sarr	9	6.7	3.8	0.9	1.6	0.2	1.1