College Football

Penn State vs. Purdue Prediction, Odds, Picks for College Football Week 9

Published Oct. 31, 2026 4:15 a.m. ET

FOX Sports Research

The Penn State Nittany Lions take on the Purdue Boilermakers on Saturday in a Week 9 college football matchup on Big Ten Network.

Let’s take a look at the odds for Purdue vs. Penn State at DraftKings Sportsbook as of Oct. 31.

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Purdue @ Penn State Odds

Moneyline

Purdue: +235
Penn State: -290

Spread

Purdue +7.5: -108
Penn State -7.5: -112

Over/Under

Over 54.5: -115
Under 54.5: -105

Purdue @ Penn State Prediction, Pick

From FOX Sports Research:

Penn State has lost four straight and has yet to beat a Power 4 team this season.
Purdue's Ryan Browne is the Big Ten's third-leading passer with 1,822 yards and Penn State's Rocco Becht is fifth with 1,664 yards.
Last time Purdue beat Penn State was 2004, also the only time the Boilermakers won at Penn State. The Nittany Lions have won 11 straight over Purdue, averaging 34 points and allowing just 14.5 points over those 11 games.