SAN FRANCISCO 49ERS PLAYER NEWS

Coach Kyle Shanahan said Pearsall (knee/ankle) will be limited at practice Wednesday, Matt Maiocco of NBC Sports Bay Area reports.

Coach Kyle Shanahan said Kittle (ankle) won't practice Wednesday but "has a chance" to play Sunday against the Bears, Nick Wagoner of ESPN.com reports.

Kittle was diagnosed with a low-to-mid-grade left ankle sprain following an MRI on Tuesday, Jeremy Fowler of ESPN.com reports.

Tonges caught one of two targets for seven yards in Monday's 48-27 win over the Colts.

Robinson rushed five times for 20 yards while failing to catch his only target in Monday's 48-27 win over Indianapolis.

Robinson had two receptions on as many targets for 22 yards and a touchdown in Monday's 48-27 win over Indianapolis.

Bourne had three receptions (on five targets) for 27 yards in Monday's 48-27 win over the Colts.

Jennings corralled five of six targets for 71 yards and a touchdown in Monday's 48-27 win over the Colts.

McCaffrey handled 21 carries for 117 yards and caught six of eight targets for 29 yards and a pair of touchdowns in Monday's 48-27 win over Indianapolis.

San Francisco coach Kyle Shanahan said after Monday's 48-27 win against the Colts that it's too early to know the severity of Kittle's ankle injury, Nick Wagoner of ESPN.com reports.

Purdy completed 25 of 34 pass attempts for 295 yards, five touchdowns and one interception while taking two carries for 11 yards in Monday's 48-27 rout of the Colts.

Kittle is dealing with an ankle injury and is questionable to return to Monday's Week 16 matchup against Indianapolis, Matt Maiocco of NBC Sports Bay Area reports.

Bourne is poised to take on a larger role against the Colts on Monday after Ricky Pearsall (knee/ankle) was officially ruled out, Matt Barrows of The Athletic reports.

Pearsall (knee/ankle) has been ruled out for Monday's game against the Colts, Matt Maiocco of NBC Sports Bay Area reports.

Pearsall (knee/ankle) isn't practicing Friday, Cam Inman of The San Jose Mercury News reports.