Panthers vs. Saints 2025 Prediction, Odds, Picks - Dec 14

The Carolina Panthers (7-6) are small favorites (-2.5) versus the New Orleans Saints (3-10) in a battle of two division rivals. An over/under of 41.5 points has been set for the matchup.

Keep up with the 2025 NFL season on FOX Sports.

Panthers vs. Saints Odds & Betting Lines

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Panthers vs. Saints Prediction & Pick

• Pick ATS: Saints (+2.5)
  
• Pick OU: Under (41.5)
  
• Prediction: Panthers 22 - Saints 19

How to Watch Carolina vs. New Orleans

• Game date: Sunday, December 14, 2025
• Time: 4:25 p.m. ET
• Venue: Caesars Superdome
• Location: New Orleans, Louisiana
• TV: Watch on FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Panthers vs. Saints Recent Matchups

• Over their last five meetings, New Orleans has collected four wins versus Carolina.
• In their last five head-to-head matchups, New Orleans has scored 134 points against Carolina, while allowing only 63 points.

Carolina Betting Info

• In 13 Carolina games this season, it has eight wins against the spread.
• The Panthers have not covered the spread this season (0-1 ATS) when playing as at least 2.5-point favorites.
• Carolina games this year have hit the over on seven of 13 set point totals (53.8%).
• The Panthers have been moneyline favorites a single other time this season, a game they lost.
• The implied probability in this matchup, considering the moneyline, gives the Panthers a 59.7% chance to win.

Panthers Stats

Carolina's Key Players

Offense

• Bryce Young has 2,337 passing yards in 12 games this year, averaging 194.8 per game with a 63.4% completion percentage and 18 touchdowns against nine interceptions.
• He has added 121 rushing yards (10.1 per game) and one touchdown on the ground.
• Rico Dowdle's rushing statline this season includes 929 yards (ninth in the NFL) and five TDs. He's averaging 71.5 yards per game and 4.8 per attempt (10th in the NFL).
• Dowdle has 29 receptions on 36 targets for 254 yards. He has one receiving TD.
• Tetairoa McMillan has six touchdown catches this season, and has 57 receptions for 826 yards on 98 targets, while averaging 4.4 catches and 63.5 yards per game.
• Chuba Hubbard has rushed for 433 yards with one touchdown (39.4 yards per game through 11 games).
• He's added 23 catches (on 32 targets) for 194 receiving yards with three touchdowns. He's averaging 17.6 receiving yards and 2.1 receptions per game.

Defense

• On the defensive side for the Panthers, Tre'von Moehrig has racked up 81 tackles, 10.0 TFL, one sack, and one interception in 2025.
• Christian Rozeboom has 91 tackles and 5.0 TFL this season.
• Derrick Brown has collected 45 tackles, 4.0 TFL, four sacks, and seven passes defended.
• Nick Scott has 73 tackles and one interception on the year.

New Orleans Betting Info

• New Orleans has registered a 5-8-0 record against the spread this year.
• The Saints have been underdogs by 2.5 points or more 11 times this season and are 4-7 ATS in those contests.
• This season, four New Orleans games have gone over the point total.
• The Saints have been underdogs in 11 games this season and won two (18.2%) of those contests.
• The moneyline for this contest implies a 44.6% chance of a victory for the Saints.

Saints Stats

New Orleans' Key Players

Offense

• So far this year, Chris Olave has 76 receptions (eighth in the NFL) for 811 yards with five receiving touchdowns. He has been targeted 120 times and averages 5.8 catches per game in 13 games played.
• Spencer Rattler has 1,586 passing yards, eight touchdowns and five interceptions. His completion percentage is 67.8% and he averages 198.3 yards per game and 6.2 per attempt.
• He has added 167 rushing yards (fourth on the Saints), while scoring zero touchdowns on the ground (averaging 20.9 yards per game and 5.4 per carry).
• Through seven games this season, Tyler Shough has racked up 1,212 passing yards, with five touchdowns against five interceptions and completing 65.2% of his passes.
• He's added 106 yards on the ground (fifth on the Saints), with two rushing touchdowns. He's averaging 15.1 yards per game and 3.8 per attempt.
• Juwan Johnson has been targeted 80 times, resulting in 58 catches for 614 yards .

Defense

• Demario Davis has 118 tackles, 5.0 TFL, and two passes defended in 2025.
• Pete Werner has 69 tackles, 4.0 TFL, and two sacks. He is second on the Saints in tackles.
• During the 2025 campaign, Kool-Aid McKinstry has 58 tackles, 3.0 TFL, and three interceptions in 13 games.
• Alontae Taylor's stat sheet includes two interceptions as well as 59 tackles, 5.0 TFL, one sack, and seven passes defended in 13 games

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

New Orleans Saints

Carolina Panthers