Lakers vs. Spurs Prediction, Odds, Picks - Dec. 10

The San Antonio Spurs (16-7) face the Los Angeles Lakers (17-6) on December 10, 2025 at Crypto.com Arena. Los Angeles is a healthy 7-point favorite against San Antonio when the Lakers play the Spurs on Wednesday. The matchup's point total is 241.5.

Check out everything you need to know to know about the Lakers-Spurs game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Lakers vs. Spurs Game Information, TV Channel & Odds

• When: Wednesday, December 10, 2025 at 10 p.m. ET
• Where: Crypto.com Arena in Los Angeles, California
• TV: Amazon Prime Video and SportsNet LA
• Live Boxscore: FOX Sports

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Lakers vs. Spurs Prediction

ATS Pick: Spurs (+ 7)
O/U Pick: Under (241.5)
Score Prediction: Lakers 118 - Spurs 116

Lakers vs. Spurs Betting Insights

• Of 23 games so far this season, the Lakers have had seven with more than 241.5 points scored, their current matchup's total.
• The Spurs have played in eight games this year (34.8% of chances) in which the teams combined to score more than 241.5 points.
• The two teams average a combined 3.6 fewer points per game (237.9) than this matchup's over/under of 241.5 points.
• Opponents of the two teams average a combined 10.1 fewer points per game (231.4) than this game's over/under of 241.5 points.
• Los Angeles has won 10, or 83.3%, of the 12 contests in which it was the favorite this year.
• San Antonio has been an underdog in eight games this season and has come away with the win five times (62.5%) in those contests.
• Los Angeles holds a 1-0 record in the last one head-to-head games against San Antonio.
• The Lakers also have a 1-0 record against the spread when playing the Spurs.

Lakers Recent Trends

• The Lakers are 6-4 against the spread and 8-2 overall over their past 10 contests.
• Los Angeles has averaged a total of 232.3 combined points over its last 10 games, 9.2 less than this matchup's over/under of 241.5.
• The Lakers have 15 wins against the spread in 23 games this season.
• So far this season, Los Angeles has been installed as favorites by a 7-point margin or more six times and are 4-2 ATS in those matchups.
• Lakers games this year have hit the over 69.6% of the time (16 out of 23 games with a set point total).
• The Lakers put up 118.3 points per game, just 3.0 more points than the 115.3 the Spurs allow.
• Los Angeles is 14-1 against the spread and 15-0 overall when scoring more than 115.3 points.
• The Lakers are shooting 50.7% from the field this season, 3.6 percentage points higher than the 47.1% the Spurs allow to opponents.
• The Lakers have covered the spread in a lower percentage of their home games than road games. They have covered six times in 10 games when playing at home, and they've covered nine times in 13 games on the road.
• Looking at point totals, Los Angeles hits the over more consistently when playing at home, as it has gone over the total 10 times in 10 opportunities this season (100%). On the road, it has hit the over six times in 13 opportunities (46.2%).
• The Lakers, as a moneyline favorite, have an identical winning percentage when playing at home (5-1 record) and on the road (5-1 record).

Lakers Recent Stats

Lakers Leaders

• Luka Doncic averages 35.0 points, 9.2 boards and 9.1 assists per contest, shooting 47.2% from the floor and 33.5% from beyond the arc with 3.6 made 3-pointers per game (third in league).
• Austin Reaves averages 28.4 points, 5.5 boards and 6.7 assists per game, shooting 50.9% from the floor and 37.0% from downtown with 2.9 made 3-pointers per contest.
• Deandre Ayton puts up 15.3 points, 8.8 boards and 0.9 assists per game, shooting 70.6% from the floor (second in league).
• Rui Hachimura averages 14.0 points, 0.8 assists and 3.9 rebounds.
• Jake Laravia posts 8.9 points, 3.8 rebounds and 1.8 assists per game. Defensively he averages 1.2 steals and 0.3 blocks.

Lakers Player Props

Spurs Recent Trends

• The Spurs have gone 7-3 in their last 10 contests, with a 6-4 record against the spread during that span.
• San Antonio and its opponents have combined to score an average of 236.0 combined points in its last 10 games, 5.5 less than the 241.5 over/under in this matchup.
• Against the spread, the Spurs are 10-10-3 this year.
• San Antonio has been underdogs by 7 points or more two times this year and has covered the spread every time.
• Spurs games this year have eclipsed the over/under 13 times in 23 opportunities (56.5%).
• The Spurs put up an average of 119.6 points per game, only 3.5 more points than the 116.1 the Lakers give up to opponents.
• San Antonio is 7-6-2 against the spread and 12-3 overall when it scores more than 116.1 points.
• The Spurs are shooting 48.5% from the field, 0.5% higher than the 48.0% the Lakers' opponents have shot this season.
• The Spurs' winning percentage against the spread at home is .545 (6-3-2). Away, it is .333 (4-7-1).
• San Antonio's games have gone above the over/under 45.5% of the time at home (five of 11), and 66.7% of the time on the road (eight of 12).
• The Spurs, when moneyline favorites, have won a higher percentage of games at home (7-2) than on the road (3-2) this season.

Spurs Recent Stats

Spurs Leaders

• Devin Vassell is averaging 15.7 points, 3.7 rebounds and 2.4 assists per contest. He's also sinking 43.7% of his shots from the field and 39.8% from 3-point range, with 2.8 triples per contest.
• The Spurs are receiving 24.3 points, 3.7 rebounds and 6.5 assists per game from De'Aaron Fox this season.
• Keldon Johnson gets the Spurs 13.0 points, 6.5 rebounds and 1.8 assists per contest while averaging 0.7 steals and 0.1 blocked shots.
• Harrison Barnes gets the Spurs 13.4 points, 3.4 rebounds and 2.2 assists per game while posting 1.0 steal and 0.2 blocked shots.
• Julian Champagnie is putting up 11.2 points, 5.3 rebounds and 1.4 assists per game. He is making 42.0% of his shots from the floor and 37.8% from beyond the arc, with 2.3 triples per game.

Spurs Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

FOLLOW Follow your favorites to personalize your FOX Sports experience

National Basketball Association

Los Angeles Lakers

San Antonio Spurs