Lakers vs. Spurs Prediction, Odds, Picks - Dec. 10

The Los Angeles Lakers (17-6) take on the San Antonio Spurs (16-7) on December 10, 2025 on Amazon Prime Video and SportsNet LA. The Lakers square off with the Spurs in a game that Los Angeles is currently a strong favorite by 7 points. The point total for the game is 241.5.

Here's everything you need to know to know about the Lakers-Spurs game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Lakers vs. Spurs Game Information, TV Channel & Odds

• When: Wednesday, December 10, 2025 at 10 p.m. ET
• Where: Crypto.com Arena in Los Angeles, California
• TV: Amazon Prime Video and SportsNet LA
• Live Boxscore: FOX Sports

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Lakers vs. Spurs Prediction

ATS Pick: Spurs (+ 7)
O/U Pick: Under (241.5)
Score Prediction: Lakers 118 - Spurs 116

Lakers vs. Spurs Betting Insights

• This year, the Lakers games have gone over 241.5 points scored, their current matchup's over/under, seven (out of 23) times.
• The Spurs have played in eight games this season (34.8% of opportunities) in which the teams combined to score more than 241.5 points.
• The two teams average a combined 3.6 fewer points per game (237.9) than this game's over/under of 241.5 points.
• Opponents of these teams have averaged a combined 231.4 points per game, 10.1 fewer than the point total in this matchup.
• Los Angeles has come away with 10 wins in the 12 contests it has been listed as the favorite this season.
• San Antonio has won in five of the eight contests it has been named as the odds-on underdog this year.
• Los Angeles has a 1-0 record in the last one head-to-head games against San Antonio.
• The Lakers also have a 1-0 record against the spread when playing the Spurs.

Lakers Recent Trends

• The Lakers are 6-4 against the spread and 8-2 overall in their last 10 games.
• Los Angeles and its opponents have combined to score an average of 232.3 points in its last 10 games, 9.2 less than the 241.5 over/under in this matchup.
• Against the spread, the Lakers are 15-8-0 this year.
• Los Angeles is 4-2 ATS when favored by 7 points or more this season.
• Lakers games this year have gone over the total in 16 out of 23 opportunities (69.6%).
• The Lakers put up just three more points per game (118.3) than the Spurs give up (115.3).
• When Los Angeles totals more than 115.3 points, it is 14-1 against the spread and 15-0 overall.
• The Lakers make 50.7% of their shots from the field this season, which is 3.6 percentage points higher than the Spurs have allowed to their opponents (47.1%).
• At home, the Lakers have a worse record against the spread (6-4-0) compared to their ATS record on the road (9-4-0).
• Los Angeles has exceeded the over/under in a higher percentage of home games (100%) than away games (46.2%).
• As a moneyline favorite, the Lakers have an identical winning percentage at home compared to away from home (.833).

Lakers Recent Stats

Lakers Leaders

• Luka Doncic posts 35 points, 9.1 assists and 9.2 boards per contest.
• Austin Reaves posts 28.4 points, 5.5 rebounds and 6.7 assists per contest. Defensively, he averages 1.1 steals and 0.2 blocks.
• Deandre Ayton averages 15.3 points, 0.9 assists and 8.8 boards per game.
• Rui Hachimura averages 14 points, 3.9 rebounds and 0.8 assists per game, shooting 53.6% from the field and 46.2% from downtown (seventh in NBA) with 2 made 3-pointers per game.
• Jake Laravia averages 8.9 points, 3.8 boards and 1.8 assists per game, shooting 46.3% from the floor and 33.3% from beyond the arc with 1 made 3-pointers per contest.

Lakers Player Props

Spurs Recent Trends

• The Spurs are 6-4 against the spread and 7-3 overall in their last 10 games.
• San Antonio has averaged a total of 236 combined points in its last 10 games, 5.5 less than this matchup's total of 241.5.
• The Spurs have played 23 games, with 10 wins against the spread.
• San Antonio has been underdogs by 7 points or more two times this season and has covered the spread every time.
• Spurs games this year have gone over the total in 13 of 23 opportunities (56.5%).
• The Spurs put up an average of 119.6 points per game, just 3.5 more points than the 116.1 the Lakers allow.
• When it scores more than 116.1 points, San Antonio is 7-6-2 against the spread and 12-3 overall.
• The Spurs are shooting 48.5% from the field, 0.5% higher than the 48% the Lakers' opponents have shot this season.
• In 2025-26 against the spread, the Spurs have a better winning percentage at home (.545, 6-3-2 record) than away (.333, 4-7-1).
• In 2025-26 a lower percentage of San Antonio's games have finished above the over/under at home (45.5%, five of 11) compared to on the road (66.7%, eight of 12).
• The Spurs' winning percentage at home when moneyline favorites is .778 (7-2), and on the road it is .600 (3-2).

Spurs Recent Stats

Spurs Leaders

• Devin Vassell provides 15.7 points, 3.7 rebounds and 2.4 assists per game for the Spurs.
• On a per-game basis, De'Aaron Fox gets the Spurs 24.3 points, 3.7 rebounds and 6.5 assists. He also averages 1.3 steals and 0.3 blocked shots.
• Keldon Johnson is averaging 13 points, 6.5 rebounds and 1.8 assists per game. He is sinking 57.5% of his shots from the floor (10th in NBA).
• Harrison Barnes is averaging 13.4 points, 3.4 rebounds and 2.2 assists per contest. He is making 49.3% of his shots from the floor and 43.3% from 3-point range, with 2.4 treys per game.
• The Spurs are receiving 11.2 points, 5.3 rebounds and 1.4 assists per game from Julian Champagnie this year.

Spurs Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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