Knicks vs. 76ers Prediction, Odds, Picks - Dec. 19

The Philadelphia 76ers (14-11) will look to Tyrese Maxey (third in NBA, 31.5 points per game) to help knock off Jalen Brunson (seventh in league, 28.7) and the New York Knicks (19-7) on December 19, 2025 at Madison Square Garden. Friday's matchup between the Knicks and the 76ers sees the Knicks as 5.5-point favorites. The over/under for the game is 229.5.

Take a look at everything you need to know about the Knicks-76ers game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Knicks vs. 76ers Game Information, TV Channel & Odds

• When: Friday, December 19, 2025 at 7 p.m. ET
• Where: Madison Square Garden in New York City, New York
• TV: Amazon Prime Video and MSG
• Live Boxscore: FOX Sports

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Knicks vs. 76ers Prediction

ATS Pick: Knicks (- 5.5)
O/U Pick: Over (229.5)
Score Prediction: Knicks 121 - 76ers 112

Knicks vs. 76ers Betting Insights

• The Knicks and their opponent have combined to score over 229.5 points, the current matchup's over/under, in 14 of 26 games this year.
• The 76ers have played in 13 games this season (52% of opportunities) in which the teams combined to score more than 229.5 points.
• These two teams average 237.5 points per game combined, eight more than the over/under of 229.5.
• Opponents of these two teams have averaged a combined 228.1 points per game, 1.4 fewer than the point total in this game.
• New York has been victorious in 18, or 78.3%, of the 23 contests it has been chosen as favorites in this season.
• Philadelphia has been chosen as underdogs in 11 games this year and has walked away with the win three times (27.3%) in those games.
• In the last four head-to-head matchups, New York has a 4-0 record against Philadelphia.
• The Knicks also have a 3-1 advantage against the spread when playing the 76ers.

Knicks Recent Trends

• The Knicks are 8-2 against the spread and 9-1 overall over their last 10 games.
• New York's average total over the last 10 games is 2.2 points more than the 229.5 over/under listed for this matchup.
• The Knicks have 16 wins against the spread in 26 games this season.
• New York has an ATS record of 11-2-1 in its 14 games when favored by 5.5 points or more so far this season.
• Knicks games this year have hit the over 14 times in 25 opportunities (56%).
• The Knicks score 120.7 points per game, just 4.9 more points than the 115.8 the 76ers allow.
• New York has a 14-3 record against the spread and a 14-3 record overall when putting up more than 115.8 points.
• The Knicks make 48% of their shots from the field this season, which is two percentage points higher than the 76ers have allowed to their opponents (46%).
• The Knicks have covered the spread in a higher percentage of their home games than away games. They have covered 13 times in 14 opportunities at home, and they've covered three times in 12 opportunities in road games.
• In terms of over/unders, New York hits the over more often at home, as it has eclipsed the total eight times in 14 opportunities this season (57.1%). In away games, it has hit the over six times in 12 opportunities (50%).
• At home, the Knicks have won more consistently as a moneyline favorite, putting up a record of 12-1 (.923). In away games, they are 6-4 (.600) as a moneyline favorite.

Knicks Recent Stats

Knicks Leaders

• Karl-Anthony Towns averages 22.4 points, 3.2 assists and 11.9 boards per contest.
• Brunson posts 28.7 points, 3.3 boards and 6.4 assists per contest, shooting 48.4% from the field and 37.6% from downtown with 2.8 made 3-pointers per game.
• Mikal Bridges posts 16.6 points, 4.7 boards and 4.2 assists per contest. At the other end, he averages 1.8 steals (fourth in league) and 1.1 blocks.
• Josh Hart averages 12.4 points, 7.7 rebounds and 5 assists per game. Defensively, he averages 1.4 steals and 0.3 blocks.
• OG Anunoby averages 16.2 points, 1.9 assists and 5.4 boards.

76ers Recent Trends

• The 76ers are 5-5 against the spread and 5-5 overall over their past 10 contests.
• Philadelphia's average total over the last 10 games is 0.8 points fewer than the 229.5 over/under given for this matchup.
• The 76ers have played 25 games, with 13 wins against the spread.
• This season, Philadelphia has one ATS win in two games as an underdog of 5.5 points or more.
• 76ers games this season have gone over the total in 12 of 25 opportunities (48%).
• The 76ers score an average of 116.8 points per game, only 4.5 more points than the 112.3 the Knicks give up.
• Philadelphia has put together an 11-4 ATS record and an 11-4 overall record in games it scores more than 112.3 points.
• The 76ers are shooting 45.2% from the field, 0.8% lower than the 46% the Knicks' opponents have shot this season.
• The 76ers' winning percentage against the spread at home is .400 (6-8-1). On the road, it is .700 (7-3-0).
• Philadelphia's games have finished above the over/under less often at home (six times out of 15) than away (six of 10) this year.
• As moneyline favorites, the 76ers have won a lower percentage of games at home (6-2) than away (5-1).

76ers Recent Stats

76ers Leaders

• Maxey delivers 31.5 points, 4.7 rebounds and 7.2 assists per game for the 76ers.
• The 76ers are receiving 16.2 points, 4.2 rebounds and 4.5 assists per game from Quentin Grimes this year.
• VJ Edgecombe is putting up 15.2 points, 5.6 rebounds and 4 assists per game. He is making 42.1% of his shots from the field and 38.8% from 3-point range, with 2 triples per game.
• The 76ers are getting 7.3 points, 9.4 rebounds and 0.9 assists per game from Andre Drummond this season.
• Joel Embiid gives the 76ers 20.5 points, 6.6 rebounds and 2.8 assists per game while averaging 0.8 steals and 1.3 blocked shots.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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