Yankees vs. Twins Prediction, Odds, Picks - September 17

Taj Bradley gets the nod for the Minnesota Twins on Wednesday at Target Field against Ben Rice and the New York Yankees. First pitch is at 7:40 p.m. ET for the final game of a three-game series. Oddsmakers list the Yankees as -158 moneyline favorites, while giving the underdog Twins +132 moneyline odds to win. New York is favored on the run line (-1.5). The total is 9 runs for the contest (with -120 odds to hit the over and +100 odds to go under).

Take a look at everything you need to know from a betting perspective on the Yankees-Twins game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Tigers vs. Yankees Highlights | MLB on FOX

Enjoy the best moments between the Detroit Tigers and the New York Yankees.

Yankees vs. Twins Game Information & Odds

• When: Wednesday, September 17, 2025 at 7:40 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: MNNT and Amazon Prime Video

Yankees vs. Twins Prediction

• Score Prediction: Yankees 6, Twins 5
• Total Prediction: Over 9 runs
• Win Probabilities: Yankees 52%, Twins 48%

Yankees vs. Twins Betting Insights

• The Yankees have won 74, or 57.8%, of the 128 games they've played as favorites this season.
• New York is 46-26 this season when entering a game favored by -158 or more on the moneyline.
• The implied probability of a win from the Yankees, based on the moneyline, is 61.2%.
• The Twins have won in 24, or 39.3%, of the 61 contests they have been named as odds-on underdogs this year.
• This year, Minnesota has won six of 17 games when listed as at least +132 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Twins have a 43.1% chance of pulling out a win.

Yankees Recent Betting Performance

• The Yankees have a 6-3 record from the nine games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 outings, the Yankees and their opponents combined to hit the over on the run total five times (all 10 games had set totals).
• The Yankees' ATS record is 4-6-0 over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Aaron Judge paces the Yankees in home runs (48), runs batted in (103) and has put up a team-high batting average of .326.
• Of all batters in baseball, Judge's home run total places him fourth, and his RBI tally puts him eighth.
• Cody Bellinger is hitting .273 with 25 doubles, five triples, 28 home runs and 48 walks.
• Bellinger is 29th in homers and 15th in RBI among all major league hitters this year.
• Trent Grisham is hitting .239 with nine doubles, a triple, 31 home runs and 73 walks.
• Jazz Chisholm is hitting .244 with 13 doubles, a triple, 29 home runs and 56 walks.

Yankees Team Props

Twins Recent Betting Performance

• The Twins have played as underdogs in five of their past 10 games and won three of those contests.
• In their last 10 games with a total, the Twins and their opponents have failed to hit the over four times.
• Over their last 10 games, the Twins are 5-5-0 against the spread.

Twins Recent Stats

Twins Player Insights

• Byron Buxton leads the squad with a batting average of .271, while leading the Twins in home runs, with 31 and runs batted in with 76.
• Buxton's home run total puts him 12th in the big leagues, and he ranks 53rd in RBI.
• Trevor Larnach is batting .254 with 22 doubles, a triple, 17 home runs and 52 walks.
• Larnach ranks 103rd among all hitters in the majors in home runs, and 111th in RBI.
• Brooks Lee has 15 doubles, a triple, 15 home runs and 30 walks while hitting .238.
• Kody Clemens is batting .214 with 11 doubles, three triples, 19 home runs and 28 walks.

Twins Team Props

Tigers vs. Yankees Highlights | MLB on FOX

Enjoy the best moments between the Detroit Tigers and the New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Minnesota Twins

New York Yankees