Yankees vs. Cardinals Prediction, Odds, Picks - August 15

Giancarlo Stanton and the New York Yankees will try to defeat Brendan Donovan and the St. Louis Cardinals at Busch Stadium on Friday at 8:15 p.m. ET. The Cardinals are listed as +121 moneyline underdogs in this matchup with the favorite Yankees (-145). New York (-1.5) is the favorite on the run line. The over/under for the game is set at 9 runs.

Here's everything you need from a betting perspective on the Yankees-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Yankees vs. Cardinals Game Information & Odds

• When: Friday, August 15, 2025 at 8:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and YES

Yankees vs. Cardinals Prediction

• Score Prediction: Yankees 5, Cardinals 4
• Total Prediction: Under 9 runs
• Win Probabilities: Yankees 50%, Cardinals 50%

Yankees vs. Cardinals Betting Insights

• The Yankees have entered the game as favorites 101 times this season and won 55, or 54.5%, of those games.
• New York has a record of 42-27, a 60.9% win rate, when favored by -145 or more by sportsbooks this season.
• The Yankees have a 59.2% chance to win this game based on the implied probability of the moneyline.
• The Cardinals have won in 32, or 50%, of the 64 contests they have been named as odds-on underdogs this year.
• This year, St. Louis has won 11 of 28 games when listed as at least +121 or worse on the moneyline.
• The Cardinals have an implied victory probability of 45.2% according to the moneyline set by oddsmakers for this matchup.

Yankees Recent Betting Performance

• The Yankees played as the moneyline favorite for eight of their last 10 games, and finished 3-5 in those matchups.
• In their last 10 outings (all 10 of them had set totals), the Yankees and their opponents combined to hit the over five times.
• The Yankees' ATS record is 3-7-0 over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Aaron Judge is the bat to watch in the Yankees lineup, leading the team in batting average (.333), home runs (38), and RBI (88).
• Of all hitters in the majors, Judge ranks fourth in homers and seventh in RBI.
• Cody Bellinger is hitting .270 with 20 doubles, five triples, 22 home runs and 37 walks.
• Bellinger ranks 31st in homers in the majors, and 27th in RBI.
• Anthony Volpe is hitting .219 with 25 doubles, four triples, 18 home runs and 40 walks.
• Volpe will look to build on his three-game hitting in this game. During his last five outings he is batting .176 with a double, a home run, three walks and three RBIs.
• Trent Grisham has nine doubles, a triple, 21 home runs and 53 walks while batting .244.
• Grisham has recorded at least one hit in three games in a row. During his last five outings he is hitting .300 with a home run, a walk and two RBIs.

Yankees Team Props

Cardinals Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by sportsbooks, the Cardinals had a record of 4-3.
• The Cardinals and their opponents have combined to hit the over four times in their last 10 games with a total.
• Over their last 10 games, the Cardinals are 4-6-0 against the spread.

Cardinals Recent Stats

Cardinals Player Insights

• Donovan is hitting .279 with 25 doubles, nine home runs and 40 walks, while getting on base at a rate of .348.
• Among all hitters in the big leagues, Donovan's home run total is 179th and his RBI tally is 130th.
• Alec Burleson is batting .282 to lead the lineup.
• Among all major league hitters, Burleson is 92nd in homers and 81st in RBI.
• Willson Contreras paces the Cardinals in home runs (16) and runs batted in (65).
• Masyn Winn has 25 doubles, eight home runs and 30 walks while hitting .264.

Cardinals Team Props

Derek Jeter & Alex Rodriguez: Are Yankees built to win a World Series this year? | MLB on FOX

Derek Jeter, Alex Rodriguez and the "MLB on FOX" Crew discussed whether they believed the New York Yankees are built to win the World Series this year after the MLB trade deadline.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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