Red Sox vs. White Sox Prediction, Odds, Picks - April 18

The Boston Red Sox and Jarren Duran will take the field against Andrew Sebastian Benintendi and the Chicago White Sox at Fenway Park on Friday, with the first pitch at 7:10 p.m. ET. Bookmakers list the Red Sox as -230 favorites on the moneyline, while giving the underdog White Sox +189 moneyline odds to win. Boston is a 1.5-run favorite (at -108 odds). The total for the game is set at 9.5 runs.

Check out everything you need to know from a betting perspective on the Red Sox-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. White Sox Game Information & Odds

• When: Friday, April 18, 2025 at 7:10 p.m. ET
• Where: Fenway Park in Boston, Massachusetts
• How to watch on TV: NESN and CHSN

Red Sox vs. White Sox Prediction

• Score Prediction: Red Sox 6, White Sox 5
• Total Prediction: Over 9.5 runs
• Win Probabilities: Red Sox 55%, White Sox 45%

Red Sox vs. White Sox Betting Insights

• This season, the Red Sox have been favored 13 times and won seven, or 53.8%, of those games.
• Boston has played as favorites of -230 or more once this season and won that game.
• The moneyline for this contest implies a 69.7% chance of a victory for the Red Sox.
• The White Sox have won in four, or 22.2%, of the 18 contests they have been named as odds-on underdogs this year.
• This season, Chicago has been a moneyline underdog of -230 or longer four times, losing every contest.
• The moneyline set for this matchup implies the White Sox have a 34.6% chance of walking away with the win.

Red Sox Recent Betting Performance

• The Red Sox were favored on the moneyline for seven of their last 10 games, and they finished 2-5 in those matchups.
• In their last 10 matchups -- all had a set run total -- the Red Sox and their opponents combined to hit the over on the total three times.
• The Red Sox have a 3-7-0 record against the spread over their past 10 games.

Red Sox Recent Stats

Red Sox Player Insights

• Alexander David Bregman paces the Red Sox in home runs (four), runs batted in (16) and has put up a team-high batting average of .321.
• Bregman's home runs rank him 30th in MLB, and he is 12th in RBI.
• Wilyer Abreu has five doubles, three home runs and 13 walks while hitting .306.
• Among all MLB hitters, Abreu is 57th in homers and 29th in RBI.
• Kristian Campbell is hitting .302 with four doubles, three home runs and 10 walks.
• Duran has four doubles, a triple, a home run and seven walks while batting .235.
• Duran is riding a four-game hitting streak into this one. During his last five outings he is hitting .190 with a double, a home run, two walks and two RBI.

Red Sox Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and won two of those contests.
• When it comes to hitting the over, the White Sox and their opponents are 2-7-1 in their last 10 games with a total.
• Over their last 10 games, the White Sox are 5-5-0 against the spread.

White Sox Recent Stats

White Sox Player Insights

• Benintendi has swatted a team-leading two long balls.
• Among all batters in the big leagues, Benintendi's home run total is 100th and his RBI tally ranks 153rd.
• Lenyn Sosa has a club-best .281 batting average.
• Sosa is 149th among all hitters in the majors in home runs, and 188th in RBI.
• Brooks Baldwin has been solid source of run production for the White Sox with two long balls and eight runs batted in.
• Luis Robert is batting .136 with a double, a home run and eight walks.

White Sox Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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