Padres vs. Rays Prediction, Odds, Picks - April 26

Ryan Pepiot gets the nod on the mound for the Tampa Bay Rays in the second of a three-game series against the San Diego Padres and Fernando Tatis Jr. on Saturday at 8:40 p.m. ET. Bookmakers list the Padres as -120 moneyline favorites, while giving the underdog Rays +100 moneyline odds to win. San Diego (-1.5) is favored on the run line. The over/under is 8 runs for this matchup (with +100 odds on the over and -120 odds to go under).

Here is everything you need to know from a betting perspective on the Padres-Rays game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Rays Game Information & Odds

• When: Saturday, April 26, 2025 at 8:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and FDSSUN

Padres vs. Rays Prediction

• Score Prediction: Padres 5, Rays 3
• Total Prediction: Under 8 runs
• Win Probabilities: Padres 58%, Rays 42%

Padres vs. Rays Betting Insights

• The Padres have entered the game as favorites 14 times this season and won 11, or 78.6%, of those games.
• San Diego has a record of 10-3 in games when oddsmakers favor them by at least -120 on the moneyline.
• The moneyline for this contest implies a 54.5% chance of a victory for the Padres.
• The Rays have come away with four wins in the 10 contests they have been listed as the underdogs in this season.
• Tampa Bay has a mark of 4-4 in contests where sportsbooks favor it by +100 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Rays have a 50% chance of pulling out a win.

Padres Recent Betting Performance

• The Padres were the moneyline favorite in four of their last 10 games, and they went 2-2 in those matchups.
• In their last 10 outings (all 10 of them had set totals), the Padres and their opponents combined to go over the run total three times.
• The Padres' record against the spread is 4-6-0 over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Tatis paces the Padres in home runs (eight), runs batted in (17) and has racked up a team-high batting average of .340.
• Of all hitters in baseball, Tatis ranks fifth in homers and 25th in RBI.
• Manny Machado has nine doubles, two home runs and 10 walks while hitting .281.
• Among all MLB hitters, Machado ranks 139th in home runs and 125th in RBI.
• Xander Bogaerts is batting .250 with eight doubles and 12 walks.
• Gavin Sheets is batting .292 with four doubles, three home runs and five walks.

Padres Team Props

Rays Recent Betting Performance

• The Rays have played as underdogs in six of their past 10 games and have gone 3-3 in those contests.
• In their last 10 games with a total, the Rays and their opponents have failed to hit the over six times.
• The Rays are 5-5-0 ATS over their last 10 games.

Rays Recent Stats

Rays Player Insights

• The Rays are led in runs batted in by Jonathan Aranda with a mark of 13, he also leads the team in hitting, posting an average of .311.
• Aranda is 53rd in home runs and 65th in RBI among all hitters in the big leagues.
• Yandy (Fernandez) Diaz has put up 13 runs batted in to lead his team.
• Diaz ranks 92nd in homers and 65th in RBI among all MLB hitters this year.
• Kameron Misner is hitting .328 with seven doubles, a triple, three home runs and five walks.
• Junior Caminero has hit a team-high five home runs.

Rays Team Props

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Check out the best moments between the Boston Red Sox and the Tampa Bay Rays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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