Orioles vs. Athletics Prediction, Odds, Picks - June 6

Lawrence Butler and the Athletics will try to knock off Ryan O'Hearn and the Baltimore Orioles when the teams meet on Friday at 10:05 p.m. ET. Bookmakers list the Orioles as -122 favorites on the moneyline, while giving the underdog Athletics +102 moneyline odds. The Orioles are a 1.5-run favorite (at +127 odds). A 10.5-run total is set in the matchup.

Here's everything you need from a betting perspective on the Orioles-Athletics game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Athletics Highlights | MLB on FOX

Check out the best moments between Minnesota Twins and Athletics.

Orioles vs. Athletics Game Information & Odds

• When: Friday, June 6, 2025 at 10:05 p.m. ET
• Where: Sutter Health Park in West Sacramento, California
• How to watch on TV: NBCS-CA and MASN2

Orioles vs. Athletics Prediction

• Score Prediction: Athletics 6, Orioles 5
• Total Prediction: Under 10.5 runs
• Win Probabilities: Orioles 51%, Athletics 49%

Orioles vs. Athletics Betting Insights

• The Orioles have been favorites in 33 games this season and won 13 (39.4%) of those contests.
• This season, the Orioles have won 11 of their 26 games, or 42.3%, when favored by at least -122 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Orioles have a 55% chance to win.
• The Athletics have been chosen as underdogs in 46 games this year and have walked away with the win 15 times (32.6%) in those games.
• This year, the Athletics have won 12 of 42 games when listed as at least +102 or better on the moneyline.
• The moneyline set for this matchup implies the Athletics have a 49.5% chance of coming away with a victory in the contest.

Orioles Recent Betting Performance

• The Orioles went 4-1 across the five games they were moneyline favorites in their last 10 matchups.
• In their last 10 matchups (all 10 of them had set totals), the Orioles and their opponents combined to hit the over two times.
• The Orioles are 5-5-0 against the spread over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• The Orioles best hitter so far this season is O'Hearn, who's hitting at a team-leading .326 rate along with nine homers and 23 RBI.
• In all of Major League Baseball, O'Hearn is 58th in homers and 128th in RBI.
• Adley Rutschman is batting .225 with seven doubles, a triple, seven home runs and 25 walks.
• Rutschman is 98th in homers in the majors, and 182nd in RBI.
• Rutschman enters this matchup looking for his fourth game in a row with a hit. In his last five games he is batting .400 with two home runs, a walk and three RBIs.
• Gunnar Henderson has 11 doubles, two triples, eight home runs and 18 walks while batting .257.
• Jackson Holliday is hitting .260 with eight doubles, two triples, seven home runs and 12 walks.

Orioles Team Props

Athletics Recent Betting Performance

• In 10 games over the last 10 matchups when set as underdogs by sportsbooks, the Athletics had a record of 1-9.
• In their last 10 games with a total, the Athletics and their opponents have combined to hit the over eight times.
• Over their last 10 games, the Athletics are 2-8-0 against the spread.

Athletics Recent Stats

Athletics Player Insights

• Jacob Wilson paces the Athletics with a .363 batting average.
• Wilson is 77th in home runs and 46th in RBI among all hitters in MLB.
• Wilson has collected a hit in six straight games. During his last 10 outings he is hitting .463 with three doubles, three home runs, three walks and seven RBIs.
• Brent Rooker is hitting .272 with 12 doubles, a triple, 13 home runs and 25 walks.
• Among all major league hitters, Rooker ranks 18th in home runs and 31st in RBI.
• Tyler Soderstrom has been solid source of run production for the Athletics with 14 long balls and 42 runs batted in.
• Butler has 19 doubles, a triple, nine home runs and 26 walks while hitting .267.

Athletics Team Props

Twins vs. Athletics Highlights | MLB on FOX

Check out the best moments between Minnesota Twins and Athletics.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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