Giants vs. Mariners Prediction, Odds, Picks - April 6

The San Francisco Giants and Seattle Mariners will play on Sunday at Oracle Park, at 4:05 p.m. ET, with Willy Adames and Julio Rodriguez among those expected to step up at the plate. Oddsmakers list the Giants as -122 moneyline favorites, while giving the underdog Mariners +102 moneyline odds. San Francisco is favored on the run line (-1.5). A 7.5-run over/under is listed for this game.

Check out everything you need to know from a betting perspective on the Giants-Mariners game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Mariners Highlights | MLB on FOX

Check out the top moments from this game between the San Francisco Giants and the Seattle Mariners!

Giants vs. Mariners Game Information & Odds

• When: Sunday, April 6, 2025 at 4:05 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: NBCS-BA and ROOT Sports NW

Giants vs. Mariners Prediction

• Score Prediction: Giants 4, Mariners 2
• Total Prediction: Under 7.5 runs
• Win Probabilities: Giants 66%, Mariners 34%

Giants vs. Mariners Betting Insights

• The Giants have been listed as the favorite four times this season and have won all of those games.
• San Francisco has been at least -122 moneyline favorites three times this season and won each of those games.
• Sportsbooks have implied with the moneyline set for this matchup that the Giants have a 55% chance to win.
• The Mariners have come away with one win in the three contests they have been listed as the underdogs in this season.
• Seattle has been listed as an underdog of +102 or more on two occasions this season and split those games.
• Bookmakers have implied with the moneyline set for this matchup that the Mariners have a 49.5% chance of pulling out a win.

Giants Player Insights

• Wilmer Flores leads the Giants in home runs (four) and runs batted in (11).
• Flores ranks fourth in homers and fourth in RBI among all hitters in baseball.
• Flores has collected a hit in three games in a row. During his last five outings he is batting .286 with two home runs and seven RBI.
• Heliot Ramos is batting .314 with three doubles, three home runs and a walk.
• Ramos is 14th in homers and 14th in RBI on the year.
• Ramos carries an eight-game streak with at least one hit into this contest. In his last eight games he is batting .314 with three doubles, three home runs, a walk and eight RBI.
• Matt Chapman is hitting .310 with two doubles, two home runs and six walks.
• Chapman has at least one base hit in three games in a row. During his last five outings he is batting .333 with two doubles, a home run, five walks and six RBI.
• Jung Hoo Lee is batting .321 with five doubles and three walks.
• Lee is riding a six-game hitting streak into this one. During his last seven outings he is batting .321 with five doubles, three walks and three RBI.

Giants Team Props

Mariners Player Insights

• Rodriguez has a team-high two home runs.
• Among all batters in the big leagues, Rodriguez's home run total is 37th and his RBI tally is 81st.
• Jorge Polanco has been a reliable source of runs this year, leading the lineup with two home runs and eight runs batted in.
• Polanco is 37th in home runs and 14th in RBI among all MLB hitters this year.
• Dylan Moore has two home runs, tops in the clubhouse.
• Randy Arozarena paces the Mariners with two home runs.

Mariners Team Props

Giants vs. Mariners Highlights | MLB on FOX

Check out the top moments from this game between the San Francisco Giants and the Seattle Mariners!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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