Cubs vs. Red Sox Prediction, Odds, Picks - July 18

Colin Rea and the Chicago Cubs will take the field against the Boston Red Sox and starting pitcher Lucas Giolito on Friday at Wrigley Field. The Cubs are -138 moneyline favorites in this matchup against the Red Sox (+117). Chicago is favored on the run line (-1.5). A 7.5-run over/under has been set for the matchup.

Check out everything you need from a betting perspective on the Cubs-Red Sox game, regarding the run line, moneyline and total, plus expert picks.

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Cubs vs. Red Sox Game Information & Odds

• When: Friday, July 18, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MLB Network, MARQ, and NESN

Cubs vs. Red Sox Prediction

• Score Prediction: Cubs 5, Red Sox 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Cubs 54%, Red Sox 46%

Cubs vs. Red Sox Betting Insights

• The Cubs have won 45, or 69.2%, of the 65 games they've played as favorites this season.
• This season Chicago has won 31 of its 43 games, or 72.1%, when favored by at least -138 on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Cubs have a 58% chance to win.
• The Red Sox have been underdogs in 33 games this season and have come away with the win 15 times (45.5%) in those contests.
• This year, Boston has won six of 14 games when listed as at least +117 or worse on the moneyline.
• The moneyline set for this matchup implies the Red Sox have a 46.1% chance of walking away with the win.

Cubs Recent Betting Performance

• The Cubs went 4-2 across the six games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Cubs combined with their opponents to hit the over on the run total four times.
• The Cubs have gone 5-5-0 against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is hitting .280 with 19 doubles, four triples, 17 home runs and 60 walks.
• In all of Major League Baseball, Tucker is 31st in homers and 26th in RBI.
• Pete Crow-Armstrong's 25 home runs pace his team.
• Crow-Armstrong is sixth in home runs in MLB, and seventh in RBI.
• Seiya Suzuki has racked up a team-best 25 home runs and 77 runs batted in.
• Suzuki is on a two-game hitting streak entering this contest. In his last five games he is hitting .300 with two doubles and a walk.
• Nico Hoerner has 18 doubles, three triples, three home runs and 21 walks while hitting .283.

Cubs Team Props

Red Sox Recent Betting Performance

• Over the past 10 games, sportsbooks have not installed the Red Sox as underdogs once.
• When it comes to hitting the over, the Red Sox and their opponents are 6-3-1 in their last 10 games with a total.
• The Red Sox have nine wins against the spread in their last 10 chances.

Red Sox Recent Stats

Red Sox Player Insights

• Ceddanne Rafaela paces the Red Sox with a .271 batting average.
• Rafaela's home run total puts him 58th in the majors, and he is 62nd in RBI.
• Rafaela carries a 10-game hitting streak into this matchup. In his last 10 games he is hitting .421 with six doubles, five home runs, a walk and 15 RBIs.
• Jarren Duran has 25 doubles, 10 triples, eight home runs and 30 walks while hitting .258.
• Duran is 152nd overall in homers and 52nd in RBI this season.
• Wilyer Abreu leads the Red Sox with 18 long balls.
• Trevor Story has sent home a team-leading 58 runs batted in.

Red Sox Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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