Cubs vs. Giants Prediction, Odds, Picks - August 28

The Chicago Cubs and Pete Crow-Armstrong head into the final of a three-game series against Jung Hoo Lee and the San Francisco Giants on Thursday at Oracle Park. The Cubs are the favorite in this one, at -130, while the underdog Giants have +110 odds to upset. Chicago is favored on the run line (-1.5). The matchup's total is set at 8.5 runs.

Here is everything you need from a betting perspective on the Cubs-Giants game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Cubs vs. Giants Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and the San Francisco Giants.

Cubs vs. Giants Game Information & Odds

• When: Thursday, August 28, 2025 at 3:45 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: NBCS-BA and MARQ

Cubs vs. Giants Prediction

• Score Prediction: Cubs 5, Giants 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Cubs 50%, Giants 50%

Cubs vs. Giants Betting Insights

• The Cubs have entered the game as favorites 95 times this season and won 60, or 63.2%, of those games.
• Chicago has a record of 49-25 in games when bookmakers favor them by at least -130 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Cubs have a 56.5% chance to win.
• The Giants have won in 27, or 48.2%, of the 56 contests they have been named as odds-on underdogs this year.
• San Francisco has a mark of 16-20 in contests where oddsmakers favor it by +110 or worse on the moneyline.
• The moneyline set for this matchup implies the Giants have a 47.6% chance of coming away with a victory in the contest.

Cubs Recent Betting Performance

• The Cubs have a 4-4 record from the eight games they were favored on the moneyline over their last 10 matchups.
• Over their last 10 matchups (all had set totals), the Cubs combined with their opponents to go over the run total four times.
• The Cubs' ATS record is 4-6-0 over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is batting .263 with 22 doubles, four triples, 21 home runs and 82 walks.
• Among all hitters in baseball, Tucker's home run total ranks him 47th, and his RBI tally puts him 50th.
• Tucker carries a five-game hitting streak into this matchup. In his last five games he is batting .368 with a double, three home runs, two walks and seven RBIs.
• Pete Crow-Armstrong has hit 28 home runs to pace his team.
• Crow-Armstrong is 13th in home runs and 18th in RBI among all MLB hitters this season.
• Crow-Armstrong has two straight games with at least one hit. During his last five outings he is hitting .250 with a double, a home run and two RBIs.
• Nico Hoerner paces the Cubs with a .290 batting average.
• Seiya Suzuki has been productive as he leads his team with 87 runs batted in.

Cubs Team Props

Giants Recent Betting Performance

• In nine games over the last 10 matchups when set as underdogs by oddsmakers, the Giants had a record of 5-4.
• In their last 10 games with a total, the Giants and their opponents have failed to hit the over five times.
• The Giants have won seven of their last 10 games against the spread.

Giants Recent Stats

Giants Player Insights

• Rafael Devers paces the Giants in home runs (27) and runs batted in (89).
• Devers' home run total puts him 16th in the majors, and he is 11th in RBI.
• Jung Hoo Lee is batting .259 with 30 doubles, 10 triples, seven home runs and 41 walks.
• Lee is 236th in homers and 148th in RBI among all major league batters this season.
• Willy Adames is hitting .222 with 18 doubles, two triples, 22 home runs and 64 walks.
• Heliot Ramos leads the team in batting average with a mark of .266.

Giants Team Props

Cubs vs. Giants Highlights | MLB on FOX

Check out the best moments between the Chicago Cubs and the San Francisco Giants.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

San Francisco Giants

Chicago Cubs