Cardinals vs. Angels Prediction, Odds, Picks - April 2

The St. Louis Cardinals and Los Angeles Angels will play on Wednesday at Busch Stadium, at 1:15 p.m. ET, with Sonny Gray and Yusei Kikuchi the starting pitchers. The Cardinals are -147 moneyline favorites in this matchup against the Angels (+123). St. Louis is the favorite on the run line (-1.5 with +144 odds). The over/under for the game is set at 8.5 runs.

Take a look at everything you need from a betting perspective on the Cardinals-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Angels vs. Cardinals Highlights | MLB on FOX

Check out the best moments between the Los Angeles Angels and the St. Louis Cardinals.

Cardinals vs. Angels Game Information & Odds

• When: Wednesday, April 2, 2025 at 1:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and FDSW

Cardinals vs. Angels Prediction

• Score Prediction: Cardinals 5, Angels 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Cardinals 52%, Angels 48%

Cardinals vs. Angels Betting Insights

• The Cardinals won 51.9% of the games last season they were the moneyline favorite (40-37).
• St. Louis had a record of 13-12 when it played as a moneyline favorite with odds of -147 or shorter last year (52%).
• Based on this game's moneyline, the Cardinals have an implied win probability of 59.5%.
• The Angels were underdogs in 130 games last season and won 54 (41.5%) of those contests.

Cardinals Player Insights

• Brendan Donovan hit .278 last season with 14 home runs and 73 RBI.
• Alec Burleson slugged 21 homers and finished with 78 RBI.
• Masyn Winn finished with a .267 average, 15 home runs and 57 RBI last season.
• Nolan Arenado collected 157 hits, posted an OBP of .325 and a .394 SLG.

Cardinals Team Props

Angels Player Insights

• Taylor Ward launched 25 home runs while slugging .426 last season.
• Jorge Soler hit .241 with 34 doubles, a triple, 21 home runs and 68 walks.
• Nolan Schanuel had 130 hits with a batting average of .250 last season.
• Jo Adell hit .207 with 15 doubles, two triples, 20 home runs and 35 walks.

Angels Team Props

Angels vs. Cardinals Highlights | MLB on FOX

Check out the best moments between the Los Angeles Angels and the St. Louis Cardinals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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St. Louis Cardinals

Los Angeles Angels